Results 41 to 50 of about 8,569 (263)
Management of Multiple Myeloma and Usage of Bortezomib: Perspective from India and Ukraine
Frontiers in Oncology, 2016 Novel treatment strategies have remarkably improved the multiple myeloma (MM) patients’ survival, with associated increased costs.A joint panel meet of international experts from India and Ukraine was held in New Delhi on 19th May 2016 focusing on: MM ...
India and Ukraine Haemato-oncology Group +12 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Generics and Context: Do Counterexamples Dissuade Acceptance of True Generic Statements?
Studies in Logic, Grammar and RhetoricThis study investigates whether the salience of counterexamples in discourse affects the acceptance of true generic statements. Building on previous theoretical and experimental work on generics, we examine whether generics are sensitive to contextual ...
Wajda Edyta, Karczewski Daniel
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Mednarodno Inovativno Poslovanje, 2020 Declining productivity of pharmaceutical innovation resulted in an increased number of mergers & acquisitions in the pharmaceutical industry. Increased investments into research & development lack the resulting increases in patentable new ...
Davor Mance +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Generics versus branded generics: A case of confusion
Indian Journal of Community and Family MedicineGeneric medicines are generally marketed under international nonproprietary names but may also be marketed by a pharmaceutical company under a brand name, i.e. branded generics.
Proteesh Rana, Rachna Gupta
doaj +1 more source
Market Exclusivity of the Originator Drugs in South Korea: A Retrospective Cohort Study
Frontiers in Public Health, 2021 Introduction: Generic entry is a well-known driver of competition and cost containment.Objectives: We aim to measure the market exclusivity of originator drugs and to determine what influences the entry of generics in South Korea.Methods: A list of ...
Kyung-Bok Son
doaj +1 more source
Generating functions for generating trees
Discrete Mathematics, 2002 This article corresponds, up to minor typo corrections, to the article submitted to Discrete Mathematics (Elsevier) in Nov. 1999, and published in its vol. 246(1-3), March 2002, pp.
Banderier, Cyril +5 more
openaire +6 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source