Results 41 to 50 of about 36,600 (302)

Management of Multiple Myeloma and Usage of Bortezomib: Perspective from India and Ukraine

open access: yesFrontiers in Oncology, 2016
Novel treatment strategies have remarkably improved the multiple myeloma (MM) patients’ survival, with associated increased costs.A joint panel meet of international experts from India and Ukraine was held in New Delhi on 19th May 2016 focusing on: MM ...
India and Ukraine Haemato-oncology Group   +12 more
doaj   +1 more source

Mergers and Acquisitions as a Consequence of Declining Innovation Productivity in Pharmaceuticals: Evidence from Croatia

open access: yesMednarodno Inovativno Poslovanje, 2020
Declining productivity of pharmaceutical innovation resulted in an increased number of mergers & acquisitions in the pharmaceutical industry. Increased investments into research & development lack the resulting increases in patentable new ...
Davor Mance   +2 more
doaj   +1 more source

Market Exclusivity of the Originator Drugs in South Korea: A Retrospective Cohort Study

open access: yesFrontiers in Public Health, 2021
Introduction: Generic entry is a well-known driver of competition and cost containment.Objectives: We aim to measure the market exclusivity of originator drugs and to determine what influences the entry of generics in South Korea.Methods: A list of ...
Kyung-Bok Son
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Generics and Context: Do Counterexamples Dissuade Acceptance of True Generic Statements?

open access: yesStudies in Logic, Grammar and Rhetoric
This study investigates whether the salience of counterexamples in discourse affects the acceptance of true generic statements. Building on previous theoretical and experimental work on generics, we examine whether generics are sensitive to contextual ...
Wajda Edyta, Karczewski Daniel
doaj   +1 more source

Generics versus branded generics: A case of confusion

open access: yesIndian Journal of Community and Family Medicine
Generic medicines are generally marketed under international nonproprietary names but may also be marketed by a pharmaceutical company under a brand name, i.e. branded generics.
Proteesh Rana, Rachna Gupta
doaj   +1 more source

Spinning off new ventures: a typology of facilitating services [PDF]

open access: yes, 2002
This study analyses the spin-out activity in seven technology transfer units, which are considered to be successes in Europe: Crealys in France, the Top Initiative of the university of Twente in the Netherlands, Leuven R&D at the KUL in Belgium, Business
Clarysse, Bart   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Connected Polish groups with ample generics

open access: yes, 2015
In this paper, we give the first examples of connected Polish groups that have ample generics, answering a question of Kechris and Rosendal. We show that any Polish group with ample generics embeds into a connected Polish group with ample generics and ...
Kaïchouh, Adriane   +1 more
core   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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