Results 31 to 40 of about 911,821 (309)

CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the {\beta}-globin locus [PDF]

, 2012
The principles underlying the architectural landscape of chromatin beyond the nucleosome level in living cells remains largely unknown despite its potential to play a role in mammalian gene regulation. We investigated the 3-dimensional folding of a 1 Mbp
Ann Dean, Bau, Bau, Bender, Bender, Botta, Chunhui Hou, Cook, Cui, de Gennes, Dekker, Dorier, Dostie, Drissen, Duan, Farrell, François Képès, Fraser, Hadjur, Handoko, Hou, Hou, Ivan Junier, Junier, Kalhor, Kiefer, Kim, Krivega, Kurukuti, Langowski, Lee, Lieberman-Aiden, Marenduzzo, Mateos-Langerak, Mukhopadhyay, Murrell, Ong, Palstra, Phillips, Ragoczy, Reuillon, Rosa, Rousseau, Ryan K. Dale, Schoenfelder, Sexton, Sexton, Simonis, Song, Song, Splinter, Stamatoyannopoulos, Strick, Tolhuis, Vakoc, Wallace, Yaffe   +56 more
core   +6 more sources

Genetic Analysis and Molecular Mapping of an All-Stage Stripe Rust Resistance Gene in Triticum aestivum-Haynaldia villosa Translocation Line V3

Journal of Integrative Agriculture, 2013
Triticum aestivum-Hayaldia villosa translocation line V3 has shown effective all-stage resistance to the seven dominant pathotypes of Puccinia striiforms f. sp. tritici prevalent in China. To elucidate the genetic basis of the resistance, the segregating
Lu HOU, Dong-fang MA, Mao-lin HU, Miao-miao HE, Yan LU, Jin-xue JING   +5 more
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source

Genetic Analysis on Seed Size of Chieh-qua by Mixture Model of Major Genes and Polygenes

Guangdong nongye kexue, 2023
【Objective】Genetic analysis of major gene and polygenes was conducted on the length, width, and quality of Chieh-qua seeds to study the genetic rules of seed size and select high-quality Chieh-qua varieties.【Method】Chieh-qua inbred line J16 (big seed ...
Yin GAO, Jiazhu PENG, Guoping WANG, Yanchun QIAO   +3 more
doaj   +1 more source

Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy [PDF]

, 2018
NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes ...
Angelico F, Angeloni A, Arca M, Bailetti D, Baratta F, Belardinilli F, Ceci F, D'Erasmo L, De Masi B, Del Ben M, Di Costanzo A, Giannini G, Girelli G, Montali A, Pastori D, Polimeni L, Sponziello M   +16 more
core   +1 more source

Gene Therapy for Autosomal Dominant Disorders of Keratin [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2005
Dominant mutations that interfere with the assembly of keratin filaments cause painful and disfiguring epidermal diseases like pachyonychia congenita and epidermolysis bullosa simplex. Genetic therapies for such diseases must either suppress the production of the toxic proteins or correct the genetic defect in the chromosome.
Lewin, Alfred S., Glazer, Peter M., Milstone, Leonard M.   +2 more
openaire   +2 more sources

Characteristics of Wetting-Induced Bacteriophage Blooms in Biological Soil Crust. [PDF]

, 2019
Biological soil crusts (biocrusts) are photosynthetic "hot spots" in deserts and cover ∼12% of the Earth's terrestrial surface, and yet they face an uncertain future given expected shifts in rainfall events.
Northen, Trent R, Roux, Simon, Swenson, Tami L, Trubl, Gareth, Van Goethem, Marc W   +4 more
core   +2 more sources

Study on microbes and antibiotic resistance genes in karst primitive mountain marshes – A case study of Niangniang Mountain in Guizhou, China

Ecotoxicology and Environmental Safety, 2022
Previous research on antibiotic resistance genes and microorganisms centered on those in urban sewage treatment plants, breeding farms, hospitals and others with serious antibiotic pollution.
Jia Ai, Yancheng Li, Yang Lv, Xiong Zhong, Jiang Li, Aijiang Yang   +5 more
doaj   +1 more source

Preparation and characterization of magnetite (Fe3O4) nanoparticles By Sol-Gel method [PDF]

, 2019
The magnetite (Fe3O4) nanoparticles were successfully synthesized and annealed under vacuum at different temperature. The Fe3O4 nanoparticles prepared via sol-gel assisted method and annealed at 200-400ºC were characterized by Fourier Transformation ...
A. Sekak, Khairunnadim, Asman, Saliza, Mustafa, Mohd K., Takai, Zakiyyu I.   +3 more
core   +1 more source

Gene Expression Dominance in Allopolyploids: Hypotheses and Models [PDF]

Trends in Plant Science, 2018
The classical example of nonadditive contributions of the two parents to allopolyploids is nucleolar dominance, which entails silencing of one parental set of ribosomal RNA genes. This has been observed for many other loci. The prevailing explanation for this genome-wide expression disparity is that the two merged genomes differ in their transposable ...
Bottani, S, Zabet, NR, Wendel, JF, Veitia, RA   +3 more
openaire   +3 more sources