Results 11 to 20 of about 548,379 (312)

Missense mutations in EDA and EDAR genes cause dominant syndromic tooth agenesis

Molecular Genetics & Genomic Medicine, 2021
Background Hypohidrotic ectodermal dysplasia (HED) is the most common form of ectodermal dysplasia and is mainly associated with mutations in the EDA, EDAR, and EDARADD responsible for the development of ectodermal‐derived structures.
Francesca Andreoni, Claudia Sgattoni, Daniela Bencardino, Oriana Simonetti, Antonino Forabosco, Mauro Magnani   +5 more
doaj   +1 more source

Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes

Scientific Reports, 2021
Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology.
Anna Esteve-Codina, Thomas P. Hofer, Dorothe Burggraf, Marion S. Heiss-Neumann, Wolfgang Gesierich, Anne Boland, Robert Olaso, Marie-Therese Bihoreau, Jean-Francois Deleuze, Winfried Moeller, Otmar Schmid, María Soler Artigas, Kathrin Renner, Jens M. Hohlfeld, Tobias Welte, Thomas Fuehner, Lukas Jerrentrup, Andreas Rembert Koczulla, Timm Greulich, Antje Prasse, Joachim Müller-Quernheim, Sumit Gupta, Christopher Brightling, Deepak R. Subramanian, David G. Parr, Umme Kolsum, Vandana Gupta, Imre Barta, Balázs Döme, János Strausz, Mariarita Stendardo, Marco Piattella, Piera Boschetto, Damian Korzybski, Dorota Gorecka, Adam Nowinski, Marc Dabad, Marcos Fernández-Callejo, David Endesfelder, Wolfgang zu Castell, Pieter S. Hiemstra, Per Venge, Elfriede Noessner, Thasso Griebel, Simon Heath, Dave Singh, Ivo Gut, Loems Ziegler-Heitbrock   +47 more
doaj   +1 more source

Variation of Dominance of Newly Arisen Adaptive Genes [PDF]

Genetics, 1997
Newly arisen adaptive alleles such as insecticide resistance genes represent a good opportunity to investigate the theories put forth to explain the molecular basis of dominance and its possible evolution. Dominance levels of insecticide resistance conferred by insensitive alleles of the acetylcholinesterase gene were analyzed in five resistant strains
Bourguet, Denis, Lenormand, Thomas, Guillemaud, Thomas, Marcel, Véronique, Fournier, Didier, Raymond, Michel   +5 more
openaire   +3 more sources

Dominant transcript expression profiles of human protein-coding genes interrogated with GTEx dataset

Scientific Reports, 2022
The discovery and quantification of mRNA transcripts using short-read next-generation sequencing (NGS) data is a complicated task. There are far more alternative mRNA transcripts expressed by human genes than can be identified from NGS transcriptome data
Kuo-Feng Tung, Chao-Yu Pan, Wen-chang Lin   +2 more
doaj   +1 more source

A possible dominant white gene in Jersey cattle [PDF]

Genetics Selection Evolution, 2001
A white heifer ("Snow") was born in 1991 from coloured registered Jersey parents. She produced six calves sired by coloured Jersey bulls: three white bull calves, two white heifer calves, and one coloured bull calf. One of the white bull calves was mated with 40 Hereford x Friesian yearling heifers (white face, predominantly black body with some white ...
Sponenberg D Phillip, Morris Chris A
openaire   +3 more sources

Further genetic heterogeneity for autosomal dominant human sutural cataracts [PDF]

, 2003
A unique sutural cataract was observed in a 4-generation German family to be transmitted as an isolated autosomal, dominant trait. Since mutations in the gamma-crystallin encoding CRYG genes have previously been demonstrated to be the most frequent ...
Graw, Jochen, Illig, T., Billingsley, G., Wjst, M., Graw, J., Rudolph, G., Klopp, N., Heon, E.   +7 more
core   +1 more source

Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
core   +1 more source

Genomic Architecture of Yield Performance of an Elite Rice Hybrid Revealed by its Derived Recombinant Inbred Line and Their Backcross Hybrid Populations

Rice, 2022
Background Since its development and wide adoption in China, hybrid rice has reached the yield plateau for more than three decades. To understand the genetic basis of heterosis in rice and accelerate hybrid rice breeding, the yield performances of the ...
Fan Zhang, Conghe Zhang, Xiuqin Zhao, Shuangbing Zhu, Kai Chen, Guixiang Zhou, Zhichao Wu, Min Li, Tianqing Zheng, Wensheng Wang, Zhi Yan, Qinyong Fei, Zhikang Li, Jinjie Chen, Jianlong Xu   +14 more
doaj   +1 more source

Inheritance of spike color in einkorn wheat (Triticum monococcum L.)

Вісник Харківського Національного Університету Імені В.Н. Каразіна: Серія Біологія, 2022
Aim: specify the spike color inheritance in einkorn wheat (Triticum monococcum L.) hybrids. Methods: reciprocal hybrids between the black-spikeed UA0300282 and white-spikeed UA0300311 cultivated einkorn accessions were created with the use of the “single
Hao Fu
doaj   +1 more source

Allele-specific silencing of dominant disease genes [PDF]

Proceedings of the National Academy of Sciences, 2003
Small interfering RNA (siRNA) holds therapeutic promise for silencing dominantly acting disease genes, particularly if mutant alleles can be targeted selectively. In mammalian cell models we demonstrate that allele-specific silencing of disease genes with siRNA can be achieved by targeting either a linked single-nucleotide polymorphism
Victor M, Miller, Haibin, Xia, Ginger L, Marrs, Cynthia M, Gouvion, Gloria, Lee, Beverly L, Davidson, Henry L, Paulson   +6 more
openaire   +2 more sources