Results 71 to 80 of about 911,821 (309)

Dominant resistance against plant viruses

open access: yesFrontiers in Plant Science, 2014
To establish a successful infection plant viruses have to overcome a defence system composed of several layers. This review will overview the various strategies plants employ to combat viral infections with main emphasis on the current status of single ...
Dryas eDe Ronde   +2 more
doaj   +1 more source

Nucleolar dominance: a model for rRNA gene silencing [PDF]

open access: yesGenes & Development, 2006
Research over the last decade has demonstrated that the regulated packaging of DNA into chromatin is fundamental to keeping genes in an active/open or a more condensed/inactive conformation. Nucleosomes, the basic repeating unit of chromatin, contain two molecules each of canonical histones, H2A, H2B, H3, and H4.
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Inheritance and Linkage of Virulence Genes in Chinese Predominant Race CYR32 of the Wheat Stripe Rust Pathogen Puccinia striiformis f. sp. tritici

open access: yesFrontiers in Plant Science, 2018
Puccinia striiformis f.sp. tritici (Pst) is the causal agent of stripe (yellow) rust on wheat. It seriously threatens wheat production worldwide.
Long Wang   +9 more
doaj   +1 more source

Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue [PDF]

open access: yesBreast Cancer Research and Treatment, 2009
Historical data have indicated the potential for the histologically-normal breast to harbor pre-malignant changes at the molecular level. We postulated that a histologically-normal tissue with "tumor-like" gene expression pattern might harbor substantial risk for future cancer development.
Chen, Dung-Tsa   +14 more
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Major genes affecting ovulation rate in sheep

open access: yesGenetics Selection Evolution, 2005
Research conducted since 1980 in relation to inheritance patterns and DNA testing of major genes for prolificacy has shown that major genes have the potential to significantly increase the reproductive performance of sheep flocks throughout the world ...
Davis George
doaj   +1 more source

Homozygosity mapping identified loci and candidate genes responsible for freezing tolerance in Camelina sativa

open access: yesThe Plant Genome, 2023
Homozygosity mapping is an effective tool for detecting genomic regions responsible for a given trait when the phenotype is controlled by a limited number of dominant or co‐dominant loci. Freezing tolerance is a major attribute in agricultural crops such
TM Shaikh   +5 more
doaj   +1 more source

Evaluation of autosomal dominant retinal dystrophy genes in an unaffected cohort suggests rare or private missense variants may often be benign. [PDF]

open access: yes, 2013
BackgroundMany genes have been reported as harboring autosomal dominant mutations causing retinal dystrophy. As newly available gene panel sequencing and whole exome sequencing will open these genes up to greater scrutiny, we assess the rate of rare ...
Gorin, Michael B, Strom, Samuel P
core   +2 more sources

Hypersensitive response to Potato virus Y in potato cultivar Sárpo Mira is conferred by the Ny-Smira gene located on the long arm of chromosome IX [PDF]

open access: yes, 2014
Potato virus Y (PVY, Potyvirus) is the fifth most important plant virus worldwide in terms of economic and scientific impact. It infects members of the family Solanaceae and causes losses in potato, tomato, tobacco, pepper and petunia production.
Hein, Ingo   +4 more
core   +4 more sources

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