Results 51 to 60 of about 391,292 (303)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Frontiers in Plant Science, 2018 Pear is an important fruit crop of the Rosaceae family and has experienced two rounds of ancient whole-genome duplications (WGDs). However, whether different types of gene duplications evolved differently after duplication remains unclear in the pear ...
Xin Qiao +6 more
doaj +1 more source
Plants, 2023 Wheat has a large and diverse repertoire of NLRs involved in disease resistance, with over 1500 NLRs detected in some studies. These NLR genes occur as singletons or clusters containing copies of NLRs from different phylogenetic clades.
Yongchao Hao +7 more
doaj +1 more source
Non-independence between markers on homoeologous chromosomes in an interspecific allopolyploid cotton RILs population [PDF]
, 2009 Cotton, as the world's main natural textile fibre, is the focus of many studies for genetic improvement of fibre quality. Two allotetraploid (AtDt genome, 2n=4X=52) species dominate world production: G.
Arioli, Tony +6 more
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Tandem Duplicate Genes in Maize Are Abundant and Date to Two Distinct Periods of Time
G3: Genes, Genomes, Genetics, 2018 Tandem duplicate genes are proximally duplicated and as such occur in similar genomic neighborhoods. Using the maize B73 and PH207 de novo genome assemblies, we identified thousands of tandem gene duplicates that account for ∼10% of the annotated genes ...
Thomas J.Y. Kono +3 more
doaj +1 more source
Divergence of gene body DNA methylation and evolution of plant duplicate genes. [PDF]
PLoS ONE, 2014 It has been shown that gene body DNA methylation is associated with gene expression. However, whether and how deviation of gene body DNA methylation between duplicate genes can influence their divergence remains largely unexplored.
Jun Wang +2 more
doaj +1 more source
A novel myeloid cell in murine spleen defined through gene profiling [PDF]
, 2019 A novel myeloid antigen presenting cell can be generated through in vitro haematopoiesis in long-term splenic stromal cocultures. The in vivo equivalent subset was recently identified as phenotypically and functionally distinct from the spleen subsets of
Dabiri GA +5 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Convergent evolution of polyploid genomes from across the eukaryotic tree of life
G3: Genes, Genomes, Genetics, 2022 By modeling the homoeologous gene losses that occurred in 50 genomes deriving from ten distinct polyploidy events, we show that the evolutionary forces acting on polyploids are remarkably similar, regardless of whether they occur in flowering plants ...
Yue Hao +7 more
doaj +1 more source