Results 231 to 240 of about 186,564 (266)

Acquisition of prokaryotic genes by fungal genomes

Trends in Genetics, 2010
The relevance of horizontal gene transfer (HGT) in eukaryotes is a matter of debate. Recent analyses have shown clear examples in some species such as Candida parapsilosis, but broader surveys are lacking. To assess the impact of HGT in the fungal kingdom, we searched for prokaryotic-derived HGTs in 60 fully sequenced genomes. Using strict phylogenomic
Marina, Marcet-Houben, Toni, Gabaldón
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Chitotriosidase and gene therapy for fungal infections

Cellular and Molecular Life Sciences, 2009
Chitotriosidase secreted by activated human macrophages has been implicated in the defence against chitin-bearing pathogens. The antifungal properties of human chitotriosidase were investigated here following retroviral vector-mediated gene transfer of the open reading frame of the chitotriosidase gene into Chinese hamster ovary cells.
Gordon-Thomson, Clare (R8937), Kumari, Asha L. (S29325), Tomkins, Lisa (S29342), Holford, Paul (R7833), Djordjevic, Julianne T., Wright, Lesley C., Sorrell, Tania C., Moore, Geoffrey P. (R15718)   +7 more
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Gene targets for fungal and mycotoxin control

Mycotoxin Research, 2006
It was initially shown that gallic acid, from hydrolysable tannins in the pelliele of walnut kernels, dramatically inhibits biosynthesis of aflatoxin byAspergillus flavus. The mechanism of this inhibition was found to take place upstream from the gene cluster, including the regulatory gene,aflR, involved in aflatoxin biosynthesis.
J H, Kim, B C, Campbell, R, Molyneux, N, Mahoney, K L, Chan, J, Yu, J, Wilkinson, J, Cary, D, Bhatnagar, T E, Cleveland   +9 more
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Fungal Gene-Encoded Peptidase Inhibitors

Current Medicinal Chemistry, 2013
Peptidases can be inhibited by natural or synthetic small-molecule compounds, or by gene-encoded, proteinaceous inhibitors. Small-molecule peptidase inhibitors have been in the spotlight of researchers and pharmaceutical companies for many years. The studies concerning gene-encoded inhibitors are less frequent. The last decade has seen a boom of fungal
V, Bauerová, I, Pichová, O, Hrusková-Heidingsfeldová   +2 more
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Fungal sex genes—searching for the ancestors

BioEssays, 2008
AbstractThe sex‐determining genes of fungi reside at one or two specialised regions of the chromosome known as the mating type (MAT) loci. The genes are sufficient to determine haploid cell identity, enable compatible mating partners to attract each other, and prepare cells for sexual reproduction after fertilisation.
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Biotechnology of Fungal Genes

2012
Identification of Fungal Pathogenicity Genes by Agrobacterium tumefaciens-Mediated Transformation, K. Maruthachalam, Junhyun Jeon, Yong-Hwan Lee, and K.V. Subbarao The Genetics and Molecular Biology of Carotenoid Biosynthesis in Mucorales, Catalina Sanz, Mahdi Shahriari, and Arturo P. Eslava Induction and Repression of Carbohydrate Degrading Enzymes in
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Fungal Genes in Plants: Impact and Potential Applications

Trends in Plant Science, 2020
Although there is accumulating evidence for the role of foreign genes in plant development and adaptation, many issues remain. A recent study by Wang et al. on a gene of fungal origin in wheatgrass disease resistance highlights the potential application of fungal genes in crop improvement and related areas.
Qia, Wang, Jinling, Huang
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Photoregulation of Fungal Gene Expression

1996
Photoresponses do not have to be mediated by fresh gene expression. Some responses are so fast that they do not allow enough time for synthesis, maturation, and transport first of the mRNA and then of the polypeptide, and for protein activity. This is the case for phototropism towards blue light, a phenomenon that has been particularly well described ...
Enrique Cerdá-Olmedo, Luis M. Corrochano   +1 more
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Identifying essential genes in fungal pathogens of humans

Trends in Microbiology, 2002
Opportunistic fungal pathogens are an important cause of fatal invasive diseases and one of the many threats facing immunocompromised patients. Because of the limitations of the antifungal therapies currently available such as their toxicity, their narrow spectrum and the emergence of resistant pathogens, there is a significant demand for a broader ...
Arnaud, Firon, Christophe, d'Enfert
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Plant genes hijacked by necrotrophic fungal pathogens

Current Opinion in Plant Biology, 2020
Plant fungal pathogens can be classified according to their lifestyles. Biotrophs feed on living tissue and constitute an economically significant group of pathogens historically. Necrotrophs, which feed on dead tissue, have become economically significant over recent decades, especially those of the Dothideomycetes, which produce necrotrophic ...
Justin D Faris, Timothy L Friesen
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