Results 211 to 220 of about 188,479 (262)

Acquisition of prokaryotic genes by fungal genomes

Trends in Genetics, 2010
The relevance of horizontal gene transfer (HGT) in eukaryotes is a matter of debate. Recent analyses have shown clear examples in some species such as Candida parapsilosis, but broader surveys are lacking. To assess the impact of HGT in the fungal kingdom, we searched for prokaryotic-derived HGTs in 60 fully sequenced genomes. Using strict phylogenomic
Marina, Marcet-Houben, Toni, Gabaldón
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Chitotriosidase and gene therapy for fungal infections

Cellular and Molecular Life Sciences, 2009
Chitotriosidase secreted by activated human macrophages has been implicated in the defence against chitin-bearing pathogens. The antifungal properties of human chitotriosidase were investigated here following retroviral vector-mediated gene transfer of the open reading frame of the chitotriosidase gene into Chinese hamster ovary cells.
Gordon-Thomson, Clare (R8937), Kumari, Asha L. (S29325), Tomkins, Lisa (S29342), Holford, Paul (R7833), Djordjevic, Julianne T., Wright, Lesley C., Sorrell, Tania C., Moore, Geoffrey P. (R15718)   +7 more
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Gene targets for fungal and mycotoxin control

Mycotoxin Research, 2006
It was initially shown that gallic acid, from hydrolysable tannins in the pelliele of walnut kernels, dramatically inhibits biosynthesis of aflatoxin byAspergillus flavus. The mechanism of this inhibition was found to take place upstream from the gene cluster, including the regulatory gene,aflR, involved in aflatoxin biosynthesis.
J H, Kim, B C, Campbell, R, Molyneux, N, Mahoney, K L, Chan, J, Yu, J, Wilkinson, J, Cary, D, Bhatnagar, T E, Cleveland   +9 more
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Fungal Gene-Encoded Peptidase Inhibitors

Current Medicinal Chemistry, 2013
Peptidases can be inhibited by natural or synthetic small-molecule compounds, or by gene-encoded, proteinaceous inhibitors. Small-molecule peptidase inhibitors have been in the spotlight of researchers and pharmaceutical companies for many years. The studies concerning gene-encoded inhibitors are less frequent. The last decade has seen a boom of fungal
V, Bauerová, I, Pichová, O, Hrusková-Heidingsfeldová   +2 more
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Fungal sex genes—searching for the ancestors

BioEssays, 2008
AbstractThe sex‐determining genes of fungi reside at one or two specialised regions of the chromosome known as the mating type (MAT) loci. The genes are sufficient to determine haploid cell identity, enable compatible mating partners to attract each other, and prepare cells for sexual reproduction after fertilisation.
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Biotechnology of Fungal Genes

2012
Identification of Fungal Pathogenicity Genes by Agrobacterium tumefaciens-Mediated Transformation, K. Maruthachalam, Junhyun Jeon, Yong-Hwan Lee, and K.V. Subbarao The Genetics and Molecular Biology of Carotenoid Biosynthesis in Mucorales, Catalina Sanz, Mahdi Shahriari, and Arturo P. Eslava Induction and Repression of Carbohydrate Degrading Enzymes in
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Photoregulation of Fungal Gene Expression

1996
Photoresponses do not have to be mediated by fresh gene expression. Some responses are so fast that they do not allow enough time for synthesis, maturation, and transport first of the mRNA and then of the polypeptide, and for protein activity. This is the case for phototropism towards blue light, a phenomenon that has been particularly well described ...
Enrique Cerdá-Olmedo, Luis M. Corrochano   +1 more
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Fungal Gene Cluster Diversity and Evolution

2017
Metabolic gene clusters (MGCs) have provided some of the earliest glimpses at the biochemical machinery of yeast and filamentous fungi. MGCs encode diverse genetic mechanisms for nutrient acquisition and the synthesis/degradation of essential and adaptive metabolites. Beyond encoding the enzymes performing these discrete anabolic or catabolic processes,
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Fungal genes involved in pentachlorophenol degradation

2013
Highly toxic compounds, as petroleum and its derivatives, solvents, alkanes, polycyclic aromatic hydrocarbons (PAHs), pesticides, fertilizers, and heavy metals, released constantly in the environment due to industrial and agricultural activities, are often highly persistent and accumulate in the environment.
DI MATTEO, ANTONIO, TESTA, ANTONINO, Van Der Lee TAJ, RAO, MARIA ANTONIETTA, Monti MM, Pedata PA   +5 more
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Regulation of a fungal avirulence gene

Trends in Plant Science, 2001
The fungal pathogen, Cladosporium fulvum, has a limited host range on tomato, and the disease, tomato leaf mold, is confined to susceptible cultivars. Products of avirulence (Avr) genes present in C. fulvum play a major role in restricting its host range because Avr gene products are recognized by resistant tomato cultivars that carry matching ...
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