Results 201 to 210 of about 2,522,112 (307)

Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host-pathogen dynamics during <i>Aspergillus fumigatus</i> infection. [PDF]

Front Microbiol
Söhnlein J, Schäuble S, Prada Salcedo J, Abboud Z, Sheta D, Hünniger-Ast K, Seif M, Einsele H, Dandekar T, Panagiotou G, Beilhack A, Loeffler J.   +11 more
europepmc   +1 more source

Efficacy and safety of ustekinumab and vedolizumab in very early‐onset inflammatory bowel disease: A multicenter study from the pediatric inflammatory bowel disease Porto Group of ESPGHAN

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective We aimed to assess vedolizumab and ustekinumab efficacy and safety in patients with very‐early onset inflammatory bowel disease (VEO‐IBD). Methods A retrospective study involving 29 European and North American sites affiliated with the IBD Porto Group of European Society for Paediatric Gastroenterology Hepatology and Nutrition ...
Luca Scarallo, Paolo Lionetti, Jaroslaw Kierkus, Lauren Collen, Victoria Riedl, Christian Jakobsen, Gemma Pujol‐Muncunill, Kaija‐Leena Kolho, Marta Velasco Rodriguez‐Belvis, Katarina Mitrova, Darja Urlep, Benedicte Pigneur, Seamus Hussey, Firas Rinawi, Jan De Laffolie, Karl Mårild, Anat Yerushalmy‐Feler, Raffi Lev Tzion, Maya Granot, Marina Aloi, Elisabeth De Greef, Christos Tzvinikos, Christoph Norden, Caterina Strisciuglio, Kwang Yang Lee, Rémi Duclaux‐Loras, Saverio Pochesci, Naire Sansotta, Pejman Rohani, Dror S. Shouval, Yael Weintraub, CEDATA Group, Carsten Posovszky, Philip Bufler, Andreas Krahl, Stephan Buderus, Almuthe Hauer, Michael Friedt, Stefan Trenkel, Martin Laass, Söhnke Dammann, Klaus Michael Keller, Thomas Lang, Anke Dick, Steffen Reinsch, Viola Schulze   +45 more
wiley   +1 more source

An inositol receptor Itr4 coordinates carbon catabolite regulation and virulence in Cryptococcus neoformans. [PDF]

PLoS Biol
Wang Y, Tancer RJ, Wear M, Jackson KM, Zhang Y, Li K, Wang J, Gao YG, Nielsen K, Casadevall A, Xue C.   +10 more
europepmc   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

JPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder, Naomi Laventhal, Raja Rabah, Jacqueline Meadow   +3 more
wiley   +1 more source

Safety Profile and Enzymatic Specificity of <i>Aspergillus cristatus</i> CCNH008 Characterized by Genomic Analysis. [PDF]

J Fungi (Basel)
Duan Y, Chen X, Huang J, Yang J, He Z, Zhai Z, Hao Y, Zheng X.   +7 more
europepmc   +1 more source

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source

A trade-off between fungal biofilm formation and persistence in the host. [PDF]

PLoS Biol
Righi SE.
europepmc   +1 more source

Disseminated histoplasmosis mimicking autoimmune hepatitis as a trigger of secondary hemophagocytic lymphohistiocytosis in a pediatric patient

JPGN Reports, EarlyView.
Abstract Patients presenting with hemophagocytic lymphohistiocytosis (HLH) are often critically ill, and rapid identification of both HLH and underlying triggers in secondary HLH is essential for successful treatment. We present a case of secondary HLH activated by disseminated histoplasmosis (DH) that mimicked autoimmune hepatitis (AIH) on liver ...
Thomas Ratchford, Talal Al Hendawi, Eumenia Castro, Pelin Cengiz, James Conway, Shelly Cook, Leanne Mansfield, Nicholas Pytel, Christine M. Seroogy, Katelyn Watkin, Jo Wilson, Jonathan Wong, Therese Woodring, Katryn N. Furuya   +13 more
wiley   +1 more source

Overexpression of <i>rttA</i> leads to activation of the fumicycline biosynthesis cluster including the O-acetyltransferase encoding <i>fccF</i>. [PDF]

Microbiol Spectr
Birštonas L, Tröger-Görler S, Bauer I, Mertens B, Schweder H, Faserl K, Brakhage AA, Gsaller F.   +7 more
europepmc   +1 more source

Illuminating Streptomyces: Raman Spectroscopy for Antibiotic Detection and Monitoring

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy provides a non‐destructive, label‐free approach for studying the chemical diversity of Streptomyces. This review presents its application from detection to chemical characterization of secondary metabolites and monitoring of biosynthetic processes.
Adéla Mikulová, Jan Bobek, Martin Kizovský, Markéta Benešová, Ota Samek, Pavlína Modlitbová, Zdeněk Pilát   +6 more
wiley   +1 more source