Results 51 to 60 of about 2,522,112 (307)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Cocultivation of Anaerobic Fungi with Rumen Bacteria Establishes an Antagonistic Relationship

mBio, 2021
Anaerobic gut fungi (Neocallimastigomycetes) live in the digestive tract of large herbivores, where they are vastly outnumbered by bacteria. It has been suggested that anaerobic fungi challenge growth of bacteria owing to the wealth of biosynthetic genes
Candice L. Swift, Katherine B. Louie, Benjamin P. Bowen, Casey A. Hooker, Kevin V. Solomon, Vasanth Singan, Chris Daum, Christa P. Pennacchio, Kerrie Barry, Vaithiyalingam Shutthanandan, James E. Evans, Igor V. Grigoriev, Trent R. Northen, Michelle A. O’Malley   +13 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Effect of Supplementing Different Types of Mother Daqu on Fungal Community and Functional Gene Succession during Fermentation of Jiang-Flavor Daqu [PDF]

Shipin Kexue
This study employed metagenomics, flavoromics, and physicochemical analysis to elucidate the regulatory mechanism of different types of mother Daqu on fungal community succession, functional gene expression, and volatile compound dynamics during the ...
SHI Hao, LI Shu, YANG Yang, WANG Hongmei, CHEN Yiping, XIAO Chen, ZHONG Xiaozhong, SHEN Caihong, WANG Jiali, LIU Junnan, ZHAO Jian, WEI Yang, WANG Songtao
doaj   +1 more source

Isolation and characterisation of two chitinase and one novel glucanase genes for engineering plant defence against fungal pathogens [PDF]

, 2006
Hydrolytic enzymes such as chitinases and glucanases are implicated in plant defense responses against fungal pathogens. These enzymes are responsible for the breakdown of chitin and glucan, two major components of the fungal cell walls.
Severgnini, Susana M.E.
core  

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Identification and analysis of in planta expressed genes of Magnaporthe oryzae

BMC Genomics, 2010
Background Infection of plants by pathogens and the subsequent disease development involves substantial changes in the biochemistry and physiology of both partners.
Mitchell Thomas K, Park Sook-Young, Park Jongsun, Kim Soonok, Lee Yong-Hwan   +4 more
doaj   +1 more source

RIPCAL: a tool for alignment-based analysis of repeat-induced point mutations in fungal genomic sequences [PDF]

, 2008
Background Repeat-induced point mutation (RIP) is a fungal-specific genome defence mechanism that alters the sequences of repetitive DNA, thereby inactivating coding genes.
Hane, J., Oliver, Richard, James K Hane, Richard P Oliver, Oliver, R.P., Hane James K, Hane, J.K., Oliver Richard P   +7 more
core   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source