Historical shifts, geographic biases, and biological constraints shape mammal species discovery
Taxonomic descriptions of mammals have become more robust from 1990 to 2025, with increased specimen sampling, broader comparisons, and more integrative methods. However, disparities remain: tropical and small‐bodied species are less comprehensively described, reflecting ongoing geographic and biological biases.
Matheus de T. Moroti +5 more
wiley +1 more source
GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection.
Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known to modulate the severity and ...
Juan M Ortiz Wilczyñski +6 more
doaj +1 more source
Differences in the gene expression profiles of haemocytes from schistosome-susceptible and -resistant biomphalaria glabrata exposed to Schistosoma mansoni excretory-secretory products. [PDF]
During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host.
Zahida Zahoor +8 more
doaj +1 more source
Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections
ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker +8 more
wiley +1 more source
Mixed Signals: T Cells as Architects of IgE Immunity
ABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Abigail L. Tierney +3 more
wiley +1 more source
The records of helminth fauna from grass frogs Rana temporaria Linnaeus, 1768 of Republic of Mordovia are provided. 16 helminth types have been discovered: 1 – Monogenea, 11 – Trematoda, and 4 – Nematoda.
I. V. Chihlyaev, A. B. Ruchin
doaj
Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta [PDF]
Preventive chemotherapy has long been practiced against nematode parasites of livestock, leading to widespread drug resistance, and is increasingly being adopted for eradication of human parasitic nematodes even though it is similarly likely to lead to ...
Bisset, Stewart A +6 more
core +4 more sources
The helminth TGF‐β mimic TGM4 activates SMAD signaling in macrophages and T cells through canonical TGF‐β receptors and the CD44 co‐receptor, through Domains 1–5 (D1‐5). In fibroblasts, which express lower levels of CD44, TGM4 binds but does not transduce a signal; furthermore, it inhibits activation by agonist ligands such as TGF‐β itself, in a manner
Kyle T. Cunningham +15 more
wiley +1 more source
Helminth parasites of sheep and goats in Eastern Ethiopia [PDF]
A two-year epidemiology study of helminths of small ruminants involved the collection of viscera from 655 sheep and 632 goats from 4 abattoirs in eastern Ethiopia.
Sissay, Menkir Mekonnen
core
The role of T cells in sepsis of distinct infectious aetiologies
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source

