Results 81 to 90 of about 12,335 (183)

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

SELECTION OF MARKER REGIONS OF GENES FOR THE MOLECULAR IDENTIFICATION OF HELMINTHS OF THE ASCARIDOIDEA SUPERFAMILY FOUND IN COD FISH

Eurasian Journal of Applied Biotechnology
In recent years, the consumption of imported fish has increased significantly in Kazakhstan, especially representatives of the cod family, which are characterized by a high level of parasitic invasion. Anisakidosis is a parasitic disease caused by nematodes of the Anisakidae family.
K.T. Jazina, R.S. Uakhit, A.M. Smagulova, D.M. Valeyeva, N.S. Manapov, L.A. Lider, A.K. Bulashev, V.S. Kiyan   +7 more
openaire   +1 more source

Influenza‐induced tuft cell expansion is associated with changes in ILC2 populations in the distal lungs of mice

Physiological Reports, Volume 14, Issue 13, July 2026.
Abstract Tuft cells act as sentinels that amplify type 2 inflammation primarily by activating type 2 innate lymphoid cells (ILC2s). Although normally absent from the distal lung, ectopic tuft cells form after severe lung injury including influenza infection in mice.
Maria Elena Gentile, Michael M. Maiden, Evelyn A. Martinez, Madeline Singh, Harshini Kelam, Nicolas P. Holcomb, Meryl Mendoza, Joanna Wong, Diana M. Abraham, Alena Klochkova, Sara Kass‐Gergi, Andrew E. Vaughan   +11 more
wiley   +1 more source

Additional file 2 of Widespread gene fusion artifacts in helminth genome annotations

Supplementary Material 2.
Collington, Emma L., Doxey, Andrew C., McConkey, Brendan J., Glerum, D. Moira   +3 more
openaire   +1 more source

SLC11A1 Gene Polymorphism in Adults Co-Infected with Helminth and Latent Tuberculosis in Yewa, Ogun State

African Journal of Biomedical Research, 2020
Mutations in the 3’UTR and D543N regions of the solute carrier 11a1 protein (SLC11A1) gene have been found to strongly increase the risk of several diseases caused by intracellular organisms such as M. tuberculosis. The aim of this study was to screen for polymorphisms in the 3’UTR and D543N regions of SLC11A1 gene with the goal of understanding the ...
Adepoju, P.O, Onile, O.S, Awobode, T, Cadmus, S.I.B, Anumudu, C.I.A   +4 more
openaire   +1 more source

Exploratory Toxicogenomic Analysis of Parasite-Related Th2 Immune Response

Parasitologia
Helminth parasites infect mammalian hosts through complex life cycles, mostly triggering T helper type 2 (Th2) immune responses characterized by interleukin-4 (IL4), interleukin-5 (IL5), and interleukin-13 (IL13) production.
Marina Ziliotto, José Artur Bogo Chies, Joel Henrique Ellwanger   +2 more
doaj   +1 more source

Signal Transducers and Activators of Transcription (STAT) Family Members in Helminth Infections

International Journal of Biological Sciences, 2011
Helminth parasites are a diverse group of multicellular organisms. Despite their heterogeneity, helminths share many common characteristics, such as the modulation of the immune system of their hosts towards a permissive state that favors their ...
Mireya Becerra-Díaz, Héctor Valderrama-Carvajal, Luis I. Terrazas
doaj  

External disturbances impact helminth–host interactions by affecting dynamics of infection, parasite traits, and host immune responses

Ecology and Evolution, 2019
External perturbations, such as multispecies infections or anthelmintic treatments, can alter host–parasite interactions with consequences on the dynamics of infection.
Isabella M. Cattadori, Ashutosh K. Pathak, Matthew J. Ferrari   +2 more
doaj   +1 more source

A type 2 immune circuit and arachidonic acid metabolism role in anti-nematode infection: evidence from transcriptome and targeted metabolome data in goat

Animal
The gastrointestinal nematode infection poses a covert threat to both humans and domestic animals worldwide, eliciting a type 2 immune response within the small intestine.
W.X. Chen, Q.X. Yan, R.Z. Zhong, S.X. Tang, J.J. Loor, Z.L. Tan   +5 more
doaj   +1 more source

Fecal Lipid Metabolites and Microbiota Alterations in Dogs With Concurrent Atopic Dermatitis and Adverse Food Reaction

Allergy, Volume 81, Issue 7, Page 2549-2552, July 2026.
Akane Hayashi, Sayaka Kakiyama, Koji Kawano, Naomi Harima‐Mizusawa, Toshihide Kobayashi, Chiaki Kaga, Koji Kobayashi, Takahisa Murata   +7 more
wiley   +1 more source