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MECHANISMS OF IMMEDIATE-EARLY GENES ACTIVATION
Медицинский вестник Юга России, 2016 In our article, we focus on molecular mechanisms of immediately early genes expression. We discuss extracellular signals that are transduced into the nucleus through a variety of signaling mechanisms to elicit changes in patterns of immediately early ...
P. P. Polyakov +2 more
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Treadmill Exercise as a Preventive Measure Against Age-Related Anxiety and Social Behavioral Disorders in Rats: When Is It Worth Starting? [PDF]
Annals of Rehabilitation Medicine, 2022 Objective To determine the appropriate time points to start regular exercise which could reduce age-related anxiety and impaired social behavior. Methods For this study, 8-week-old male Wistar rats were divided into three groups: no exercise (NoEX ...
Satoru Taguchi +5 more
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Distress Regulates Different Pathways in the Brain of Common Carp: A Preliminary Study
Animals, 2021 In this study, a stress trial was conducted with common carp, one of the most important species in aquaculture worldwide, to identify relevant gene regulation pathways in different areas of the brain.
Alexander Burren, Constanze Pietsch
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Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus
Neurobiology of Disease, 2022 Synapse dysfunction and loss are central features of neurodegenerative diseases, caused in part by the accumulation of protein oligomers. Amyloid-β, tau, prion, and α-synuclein oligomers bind to the cellular prion protein (PrPC), resulting in the ...
Daniel Ojeda-Juárez +17 more
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Brazilian Journal of Medical and Biological Research, 2023 Intense stimulation of most living cells triggers the activation of immediate early genes, such as Fos and Jun families. These genes are important in cellular and biochemical processes, such as mitosis and cell death.
A.C. Mosini +9 more
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The Immediate Early Response of Lens Epithelial Cells to Lens Injury
Cells, 2022 Cataracts are treated by lens fiber cell removal followed by intraocular lens (IOL) implantation into the lens capsule. While effective, this procedure leaves behind numerous lens epithelial cells (LECs) which undergo a wound healing response that ...
Samuel G. Novo +5 more
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Embryonic stem cells become mechanoresponsive upon exit from ground state of pluripotency [PDF]
Open Biology, 2019 Stem cell fate decisions are driven by a broad array of signals, both chemical and mechanical. Although much progress has been made in our understanding of the impact of chemical signals on cell fate choice, much less is known about the role and ...
C. M. Verstreken +3 more
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Brain and Behavior, 2020 Introduction Richardson's ground squirrels use alarm calls to warn conspecifics about potential predatory threats. Chirp calls typically indicate high levels of threat from airborne predators, while whistle calls are associated with lower levels of ...
Angela R. Freeman +2 more
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Neural activation following offensive aggression in Japanese quail
Biology Open, 2018 Aggression is a fundamental part of animal social behaviour. In avian species, little is known about its neural representation. In particular, neural activity following offensive aggression has not been studied in detail.
Cornelia Voigt +2 more
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The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons
Advanced Science, 2023 Lysine demethylase KDM7A removes histone modifications H3K9me1/2 and H3K27me1/2. KDM7A plays critical roles in gene expression and contribute to biological processes including tumorigenesis, metabolism, and embryonic development.
Yifan Wang +4 more
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