Results 11 to 20 of about 942 (191)
Role for Chromatin Remodeling Factor Chd1 in Learning and Memory
Precise temporal and spatial regulation of gene expression in the brain is a prerequisite for cognitive processes such as learning and memory. Epigenetic mechanisms that modulate the chromatin structure have emerged as important regulators in this ...
Ines Schoberleitner +12 more
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Functional recruitment of newborn hippocampal neurons after experimental stroke
The adult brain responds to diverse pathologies such as stroke with increased generation of neurons in the dentate gyrus of the hippocampus. However, only little is known regarding the functional integration of newborn neurons into pre-existing neuronal ...
Christiane S. Geibig +2 more
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Molecular Mechanisms of Memory Consolidation That Operate During Sleep
The role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is of central importance for memory consolidation. Less clear are the underlying molecular
Irene Reyes-Resina +6 more
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Identification of the Immediate-Early Genes of Cyprinid Herpesvirus 2
Cyprinid herpesvirus 2 (CyHV-2), which infects goldfish and crucian carp causing high mortality, is an emerging viral pathogen worldwide. The genome of CyHV-2 is large and comprises double-stranded DNA, including several genes similar to cyprinid ...
Ruizhe Tang +4 more
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Retrosplenial cortex in spatial memory: focus on immediate early genes mapping
The ability to form, retrieve and update autobiographical memories is one of the most fascinating features of human behavior. Spatial memory, the ability to remember the layout of the external environment and to navigate within its boundaries, is closely
Edyta Balcerek +2 more
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Immediate early genes (IEGs) are coordinately activated in response to neuronal activity and can cause activation of secondary response genes that modulate synaptic plasticity and mediate long-lasting changes in behaviour.
Alena Kalinina +4 more
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Profile of GABAergic interneuron activity after pilocarpine-induced status epilepticus (SE) was examined in the rat hippocampal dentate gyrus by analyzing immediate early gene expression and recording spontaneous firing at near resting membrane potential.
Xiaochen eWang +4 more
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Stressor controllability modulates the stress response in fish
Background In humans the stress response is known to be modulated to a great extent by psychological factors, particularly by the predictability and the perceived control that the subject has of the stressor.
Marco Cerqueira +9 more
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Episodic memory reflects the capacity to recollect what, where and when a specific event happened in an integrative manner. Animal studies have suggested that the medial temporal lobe and the medial pre-frontal cortex are important for episodic-like ...
Flávio F Barbosa +7 more
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Striatal NELF-mediated RNA polymerase II stalling controls l-dopa induced dyskinesia
Long-term l-3,4-dihydroxyphenylalanine (l-Dopa) treatment in Parkinson's disease leads to involuntary movements called dyskinesia, notably through an overexpression of immediate-early genes (IEG).
Matthieu F. Bastide +3 more
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