Results 11 to 20 of about 942 (191)

Role for Chromatin Remodeling Factor Chd1 in Learning and Memory

open access: yesFrontiers in Molecular Neuroscience, 2019
Precise temporal and spatial regulation of gene expression in the brain is a prerequisite for cognitive processes such as learning and memory. Epigenetic mechanisms that modulate the chromatin structure have emerged as important regulators in this ...
Ines Schoberleitner   +12 more
doaj   +1 more source

Functional recruitment of newborn hippocampal neurons after experimental stroke

open access: yesNeurobiology of Disease, 2012
The adult brain responds to diverse pathologies such as stroke with increased generation of neurons in the dentate gyrus of the hippocampus. However, only little is known regarding the functional integration of newborn neurons into pre-existing neuronal ...
Christiane S. Geibig   +2 more
doaj   +1 more source

Molecular Mechanisms of Memory Consolidation That Operate During Sleep

open access: yesFrontiers in Molecular Neuroscience, 2021
The role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is of central importance for memory consolidation. Less clear are the underlying molecular
Irene Reyes-Resina   +6 more
doaj   +1 more source

Identification of the Immediate-Early Genes of Cyprinid Herpesvirus 2

open access: yesViruses, 2020
Cyprinid herpesvirus 2 (CyHV-2), which infects goldfish and crucian carp causing high mortality, is an emerging viral pathogen worldwide. The genome of CyHV-2 is large and comprises double-stranded DNA, including several genes similar to cyprinid ...
Ruizhe Tang   +4 more
doaj   +1 more source

Retrosplenial cortex in spatial memory: focus on immediate early genes mapping

open access: yesMolecular Brain, 2021
The ability to form, retrieve and update autobiographical memories is one of the most fascinating features of human behavior. Spatial memory, the ability to remember the layout of the external environment and to navigate within its boundaries, is closely
Edyta Balcerek   +2 more
doaj   +1 more source

Effect of repeated seizures on spatial exploration and immediate early gene expression in the hippocampus and dentate gyrus

open access: yesIBRO Neuroscience Reports, 2022
Immediate early genes (IEGs) are coordinately activated in response to neuronal activity and can cause activation of secondary response genes that modulate synaptic plasticity and mediate long-lasting changes in behaviour.
Alena Kalinina   +4 more
doaj   +1 more source

Persistent Hyperactivity of Hippocampal Dentate Interneurons after a Silent Period in the Rat Pilocarpine Model of Epilepsy

open access: yesFrontiers in Cellular Neuroscience, 2016
Profile of GABAergic interneuron activity after pilocarpine-induced status epilepticus (SE) was examined in the rat hippocampal dentate gyrus by analyzing immediate early gene expression and recording spontaneous firing at near resting membrane potential.
Xiaochen eWang   +4 more
doaj   +1 more source

Stressor controllability modulates the stress response in fish

open access: yesBMC Neuroscience, 2021
Background In humans the stress response is known to be modulated to a great extent by psychological factors, particularly by the predictability and the perceived control that the subject has of the stressor.
Marco Cerqueira   +9 more
doaj   +1 more source

Differential cortical c-Fos and Zif-268 expression after object and spatial memory processing in a standard or episodic-like object recognition task

open access: yesFrontiers in Behavioral Neuroscience, 2013
Episodic memory reflects the capacity to recollect what, where and when a specific event happened in an integrative manner. Animal studies have suggested that the medial temporal lobe and the medial pre-frontal cortex are important for episodic-like ...
Flávio F Barbosa   +7 more
doaj   +1 more source

Striatal NELF-mediated RNA polymerase II stalling controls l-dopa induced dyskinesia

open access: yesNeurobiology of Disease, 2016
Long-term l-3,4-dihydroxyphenylalanine (l-Dopa) treatment in Parkinson's disease leads to involuntary movements called dyskinesia, notably through an overexpression of immediate-early genes (IEG).
Matthieu F. Bastide   +3 more
doaj   +1 more source

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