Results 151 to 160 of about 357,256 (185)
Some of the next articles are maybe not open access.
Immunoglobulin genes in Primates
Molecular Immunology, 2018Five classes of immunoglobulins are known to exist in mammals. The number of isotypes of classes G, E and A varies among species for unknown reasons. Here, a study of the presence of immunoglobulin genes in Primates was carried out from the genomes and transcriptomes deposited in the NCBI repository.
David N. Olivieri +1 more
openaire +2 more sources
The immunoglobulins and immunoglobulin genes of swine
Veterinary Immunology and Immunopathology, 1994The historical works describing the characterization of swine immunoglobulins are reviewed. The three major isotypes, IgM, IgA and IgG, have been recognized for 25 years and their concentrations in various body fluids, the location of the plasma cells throughout the body which synthesize them and their transport into lacteal secretions and absorption ...
J E, Butler, W R, Brown
openaire +2 more sources
Equine immunoglobulins and organization of immunoglobulin genes
Developmental & Comparative Immunology, 2015Our understanding of how equine immunoglobulin genes are organized has increased significantly in recent years. For equine heavy chains, 52 IGHV, 40 IGHD, 8 IGHJ and 11 IGHC are present. Seven of these IGHCs are gamma chain genes. Sequence diversity is increasing between fetal, neonatal, foal and adult age.
Stefanie, Walther +3 more
openaire +2 more sources
Immunoglobulin mRNA and Immunoglobulin Genes
1976The genetic origin of antibody diversity has been a subject of much thought and controversy over the past 20 years. Extensive studies of immunoglobulins, particularly at the amino acid sequence level, have provided us with a general scheme of the genetic loci which encode antibody molecules (Fig. 1).
C. Milstein +5 more
openaire +1 more source
Immunoglobulin Gene Diversification by Gene Conversion
1993Publisher Summary This chapter discusses recent advances in the study of gene conversion, primarily in the chicken, and on current models for the molecular mechanism of this form of somatic gene conversion. Most of the higher vertebrates, including teleost fish, the amphibian Xenopus, the reptile Caiman, and most of the mammalian species studied ...
W T, McCormack +2 more
openaire +2 more sources
Immunoglobulin Variable Region Genes
Pathology and Immunopathology Research, 1984The picture that emerges of a V gene locus, albeit still sketchy, is one of a continuously evolving region, subject on occasion to quite dramatic flux due to the operation of gene conversion, transposing elements, recombination and unequal crossing over.
openaire +2 more sources
Immunoglobulins and immunoglobulin genes of the horse
Developmental & Comparative Immunology, 2006Antibodies of the horse were studied intensively by many notable immunologists throughout the past century until the early 1970's. After a large gap of interest in horse immunology, additional basic studies on horse immunoglobulin genes performed during the past 10 years have resulted in new insights into the equine humoral immune system. These include
openaire +2 more sources
Transgenic Mice With Immunoglobulin Genes
Annual Review of Immunology, 1987Immunoglobulin (Ig) genes encode antibody molecules expressed exclu sively in the B-Iymphocyte lineage. The most immature identifiable cells of the B-cell lineage, pre-B cells, give rise to B cells that differentiate terminally into antibody secreting plasma cells.
openaire +2 more sources