The Cryptococcus neoformans STE11α gene is similar to other fungal mitogen‐activated protein kinase kinase kinase (MAPKKK) genes but is mating type specific [PDF]
Partial sequence analysis of the Cryptococcus neoformans MATα mating type locus revealed the presence of a gene with substantial sequence similarity to other fungal mitogen‐activated protein (MAP) kinase kinase kinase (MAPKKK) genes. The C. neoformans gene, designated STE11α, showed the highest degree of similarity to the Neurospora crassa nrc‐1 ...
D L, Clarke +4 more
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Autophagy Regulates Fungal Virulence and Sexual Reproduction in Cryptococcus neoformans
Autophagy (macroautophagy) is an evolutionarily conserved degradation pathway involved in bulk degradation of cytoplasmic organelles, old protein, and other macromolecules and nutrient recycling during starvation.
Su-Ting Jiang +10 more
doaj +1 more source
Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. [PDF]
Cryptococcus neoformans is a fungal human pathogen with a bipolar mating system. It undergoes a dimorphic transition from a unicellular yeast to hyphal filamentous growth during mating and monokaryotic fruiting. The traditional sexual cycle that leads to
Xiaorong Lin +3 more
doaj +1 more source
Allelic exchange of pheromones and their receptors reprograms sexual identity in Cryptococcus neoformans. [PDF]
Cell type specification is a fundamental process that all cells must carry out to ensure appropriate behaviors in response to environmental stimuli.
Brynne C Stanton +4 more
doaj +1 more source
Novel species of Huntiella from naturally-occurring forest trees in Greece and South Africa [PDF]
Huntiella species are wood-infecting, filamentous ascomycetes that occur in fresh wounds on a wide variety of tree species. These fungi are mainly known as saprobes although some have been associated with disease symptoms.
FeiFei Liu +6 more
doaj +3 more sources
White cells facilitate opposite- and same-sex mating of opaque cells in Candida albicans. [PDF]
Modes of sexual reproduction in eukaryotic organisms are extremely diverse. The human fungal pathogen Candida albicans undergoes a phenotypic switch from the white to the opaque phase in order to become mating-competent.
Li Tao +6 more
doaj +1 more source
Discovery of a modified tetrapolar sexual cycle in Cryptococcus amylolentus and the evolution of MAT in the Cryptococcus species complex. [PDF]
Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type locus (MAT). The human fungal pathogenic and basidiomycetous yeast Cryptococcus neoformans has evolved a bipolar mating system (a, α) in which the MAT locus ...
Keisha Findley +7 more
doaj +1 more source
Fungal hyphal chemotropism has been shown to be a major contributor to host-pathogen interactions. Previous studies on Fusarium species have highlighted the involvement of the Ste2 G-protein-coupled receptor (GPCR) in mediating polarized hyphal growth ...
Tanya Sharma +6 more
doaj +1 more source
Fungal mating type genes — regulators of sexual development
The mating type genes of the fungi determine sexual compatibility between different haploid individuals. In both ascomycetes and basidiomycetes the genes are seen to influence directly or indirectly the expression of developmentally regulated genes. Mating type genes from several species have now been cloned and sequenced and alternative forms within ...
Kües, U. +3 more
openaire +2 more sources
Comparative Genomic Analysis of Human Fungal Pathogens Causing Paracoccidioidomycosis [PDF]
Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally ...
Marcin Grynberg +176 more
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