Results 101 to 110 of about 1,721,302 (204)
Identification of MYC synthetic lethal genes and networks
SUMMARY MYC is a potent oncogene that is frequently overexpressed in human tumors arising in different tissues. To date there are no approved therapies to directly antagonize oncogenic MYC and its role in driving tumorigenesis. As an alternative approach we employed genetic screens using CRISPR and shRNA to identify the genes that are ...
Timothy D. Martin +5 more
openaire +2 more sources
Case report: CD8 positive T-cell Prolymphocytic Leukemia presenting complex karyotype with a rare chromosomal abnormality der(2)t(1;2)(q21;q37) and additional signals of the genes MYC, IGH, and TP53. [PDF]
Hematol Transfus Cell TherJamur VR +3 more
europepmc +1 more source
Molecular changes during AT/RT progression associated with epithelial-mesenchymal transition and extracellular matrix changes. [PDF]
Acta NeuropatholAltendorf L +14 more
europepmc +1 more source
A Multistep Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma. [PDF]
Cancer ResXu X +23 more
europepmc +1 more source
Multiple myeloma: A tale of deregulated transcription factors. [PDF]
HemasphereGómez-Echarte N +5 more
europepmc +1 more source
Corrigendum: Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice. [PDF]
Genes DevSoucek L +7 more
europepmc +1 more source
Identification of c-Myc responsive genes using rat cDNA microarray
, 2000 c-Myc functions through direct activation or repression of transcription. Using cDNA microarray analysis, we have identified c-Myc-responsive genes by comparing gene expression profiles between c-myc null and c-myc wild-type rat fibroblast cells and ...
Liu, Edison T. +9 more
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