Results 91 to 100 of about 1,721,302 (204)

Identification of key genes related to lymphangiogenesis in venous thromboembolism through transcriptomics and verification by RT-qPCR

Frontiers in Medicine
BackgroundVenous thromboembolism (VTE), a life-threatening cardiovascular disorder, involves complex interactions between thrombosis and immune dysregulation. Lymphangiogenesis-related genes (LRGs) may directly induce thrombosis by regulating endothelial
Yusheng Lin, Yusheng Lin, Jiahan Wu, Pucheng Wang, Xiaodong Lin, Hongwei Yang, Hongwei Yang   +6 more
doaj   +1 more source

An immunohistochemical study of beta-catenin in HNPCC colon tumours [PDF]

, 2004
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core   +1 more source

GSEA of MYC target genes in tumors characterized for MYC protein expression;

, 2012
(A). Gene Set Enrichment Analysis (GSEA) of all primary DLBCL cases reveals coordinate upregulation of MYC and MYC target genes (black vertical lines) in tumors with >50% MYC positive tumor nuclei (including MYC translocation-positive and –negative cases)
Margaret A. Shipp (171976), Geraldine S. Pinkus (171973), Michael J. Kluk (171954), Papiya Sinha (171956), Alyssa Roy (171958), Donna S. Neuberg (171966), Stefano Monti (171969), Scott J. Rodig (121834), Paola Dal Cin (171962), Bjoern Chapuy (171955)   +9 more
core   +1 more source

Alteraciones del gen c-Myc en la oncogénesis = c-Myc gene alterations in oncogenesis

Iatreia, 2011
La familia de protooncogenes MYC (c-Myc, N-Myc y L-Myc) se relaciona con el origen de diversas neoplasias en seres humanos. Estos genes actúan como factores de transcripción y participan en la regulación del ciclo celular, la proliferación y ...
Ospina Pérez, Mariano, Muñetón Peña, Carlos Mario   +1 more
doaj  

The Human myc Gene Family

Cold Spring Harbor Symposia on Quantitative Biology, 1986
F W, Alt, R, DePinho, K, Zimmerman, E, Legouy, K, Hatton, P, Ferrier, A, Tesfaye, G, Yancopoulos, P, Nisen   +8 more
openaire   +2 more sources

Control of Cell Proliferation by Myc Family Genes

Molecules and Cells, 1999
The c-myc proto-oncogene was discovered as the cellular homologue of the transforming oncogene of several chicken retroviruses. It has become clear that c-myc is a member of a small gene family; members of this family encode transcription factors of the Helix-loop-Helix family of transcription factors that can both activate and repress transcription ...
openaire   +2 more sources

Indirect targeting of MYC and direct targeting in combination with chemotherapies are more effective than direct mono-targeting in triple negative breast cancer

Translational Oncology
MYC amplification is disproportionally elevated in triple-negative breast cancer (TNBC) compared to other subtypes of breast cancer. Indeed, MYC has long been considered an undruggable oncogene using conventional drug design strategies or small molecules.
Negesse Mekonnen, Hobin Yang, Nirmal Rajasekaran, Kyoung Song, Yoon-La Choi, Young Kee Shin   +5 more
doaj   +1 more source

Gene model for the ortholog Myc in Drosophila ananassae.

microPublication biology
Gene model for the ortholog of Myc ( Myc ) in the May 2011 (Agencourt dana_caf1/DanaCAF1) Genome Assembly (GenBank Accession: GCA_000005115.1 ) of Drosophila ananassae . This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus Drosophila ...
Myers, Abigail, Hoffman, Alexa, Natysin, Mindy, Arsham, Andrew M, Stamm, Joyce, Thompson, Jeffrey S., Rele, Chinmay P., Reed, Laura K   +7 more
openaire   +2 more sources

MYC overexpression in natural killer cell lymphoma: prognostic and therapeutic implications

Haematologica
The current clinical management of Extranodal NK/T-cell lymphoma (ENKTL) primarily depends on conventional chemotherapy and radiotherapy, underscoring the need for innovative therapeutic strategies.
Chengfeng Bi, Yuhua Huang, Roshia Ali, Fang Wang, Xia Yang, Alyssa Bouska, Lu Xu, Xinbao Hao, Matthew A. Lunning, Wing C. Chan, Javeed Iqbal, Dennis D. Weisenburger, Julie M. Vose, Kai Fu   +13 more
doaj   +1 more source

MYC Gene [PDF]

, 2020
openaire   +1 more source