Results 81 to 90 of about 1,721,302 (204)
MYC inhibits migration of lung cancer cell lines by down-regulating AKR1C1 expression [PDF]
Jichu yixue yu linchuangObjective To explore the role of MYC in lung cancer cell migration and reveal the mechanism affecting migration. Methods siRNA MYC or pRK5-MYC plasmid was transfected into lung cancer cells A549. Cell migration was examined by wound healing assay.
JIA Kun, ZHOU Yanyan
doaj +1 more source
Gene Expression in Neuroblastoma [PDF]
, 1996 The aim of this project is to identify potential target genes (NTG's) which may be regulated by in the cell line SK-N-SH which has no amplification of theoncogene N-myc.
Said, Sohair S.S.
core
Expression and regulation of N-Myc Downstream- Regulated gene 1 in squamous cell carcinoma of the oesphagus [PDF]
, 2009 Squamous cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where the incidence is frequently high and access to health care facilities is often limited.
Bracher, Jacqueline Claire
core +1 more source
, 2013 The preimplantation mammalian embryo is sensitive to the environment in which they develop and grow, either in vivo or in vitro. Disturbance to embryo environmental conditions can affect embryo growth.
Bakheet, Ayat
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The Promyelocytic Leukaemia gene product PML interacts with Myc and influences the expression of Myc target genes [PDF]
, 2004 c-myc is a well-known proto-oncogene encoding a transcription factor that needs to be tightly regulated in order to preserve cell homeostasis. The Promyelocytic Leukaemia gene product PML plays an important role in cell growth and survival, and resides in discrete sub-nuclear structures called Nuclear Bodies (NB).
openaire +1 more source
Acta Neuropathologica CommunicationsMYC dysregulation is pivotal in the onset and progression of IDH-mutant gliomas, mostly driven by copy-number alterations, regulatory element alterations, or epigenetic changes.
Ege Ülgen +6 more
doaj +1 more source
MYC as therapeutic target in leukemia and lymphoma [PDF]
, 2015 MYC is a transcription factor that is involved in the expression of many genes. Deregulated MYC is found in about half of human tumors, being more prevalent in hematological neoplasms.
Albajar Molera, Marta +4 more
core +1 more source
Multi-scale genomic, transcriptomic and proteomic analysis of colorectal cancer cell lines to identify novel biomarkers [PDF]
, 2015 This work was partially funded by the Strategic Educational Pathways Scholarship (Malta). The scholarship is part-financed by the European Union – European Social Fund (ESF) under Operational Programme II – Cohesion Policy 2007-2013, “Empowering People ...
Briffa, Romina +23 more
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Functional analysis of N-MYC downstream regulated gene 1 (NDRG1) in Oesophageal squamous cell carcinoma [PDF]
, 2009 Oesophageal squamous cell carcinoma (OSCC) ranks as one of the deadliest tumours with a high incidence in developing countries in the areas of Southern Africa, Middle East and Far East.
Wei, Wei
core +1 more source
Augmentation of Myc-Dependent Mitotic Gene Expression by the Pygopus2 Chromatin Effector
Cell Reports, 2018 Summary: Mitotic segregation of chromosomes requires precise coordination of many factors, yet evidence is lacking as to how genes encoding these elements are transcriptionally controlled.
Phillip G.P. Andrews +3 more
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