Results 191 to 200 of about 255,591 (268)

Molecular Characterization of <i>TP53</i> Variants in Exons 4-8 and p53 Immunoexpression in a Mexican Colorectal Cancer Cohort. [PDF]

Cancers (Basel)
García-Ayala FD, Ayala-Madrigal ML, Peregrina-Sandoval J, Moreno-Ortiz JM, González-Mercado A, Franco-Topete RA, Valenzuela-Pérez JA, Macías-Gómez NM, Flores-López BA, Gutiérrez-Angulo M.   +9 more
europepmc   +1 more source

From Metabolic Crisis to Molecular Classification: Multidisciplinary Management of Synchronous Endometrioid Ovarian and Endometrial Carcinomas With Massive Tumor Burden

Cancer Nexus, EarlyView.
Managing massive tumor burden in synchronous endometrioid carcinomas. The graphical abstract summarizes the clinical pathway from presentation with massive ascites, pleural effusion, and critical metabolic abnormalities to multidisciplinary stabilization, surgical management, integrated morphologic–molecular classification, and shared decision‐making ...
Anna Homeniuk, Leena Abdalla, Sharon Fitzgerald   +2 more
wiley   +1 more source

The regulatory roles of non-coding RNAs in aerobic glycolysis and therapeutic potential in pancreatic ductal adenocarcinoma. [PDF]

Ann Med
Fan Y, Tang X, Li S, Liu S, Fang Y, Sun X, Xue Z, Niu H, Chen Y, Dai C, Ling R.   +10 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Eprenetapopt in combination with Palbociclib exerts synthetic lethality in mantle cell lymphoma. [PDF]

Transl Oncol
Dong L, Zhang Y, Chen F, Jiang W, Qian S, Song W, Yang S, Wu X, Li Z, Zhang M.   +9 more
europepmc   +1 more source

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Genetic Landscape of Oral Carcinoma Cuniculatum and its Histological Mimics. [PDF]

Head Neck Pathol
Ono S, Fukawa Y, Hirose K, Hori Y, Motooka D, Harada H, Morii E, Toyosawa S, Ishimaru N, Yamamoto H.   +9 more
europepmc   +1 more source

Vicatia thibetica de Boiss Crude Polysaccharide Delay the Aging of the Heart and Kidneys

Food Bioengineering, EarlyView.
Vicatia thibetica de Boiss crude polysaccharide (VTCP) attenuates cardiorenal aging by reducing oxidative stress, suppressing inflammation, and alleviating fibrosis. In naturally aged mice, VTCP remodels the gut microbiota, enriching beneficial short‐chain fatty acid‐producing bacteria. We propose that VTCP protects the heart and kidneys via modulation
Daoxu Zhang, Chengyi Wu, Zhiyang Ding, Yunyu Hong, Yehan Lu, Kunpeng Zhou, Ruixuan Deng, Laijia Li, Chao Li, Yongcheng Yang, Conglong Xia, Jian Li, Wenwen Liu, Faliang An, Zelan Hu   +14 more
wiley   +1 more source

High-throughput strategy for targeting MDM2 in uveal melanoma to reverse radiation therapy resistance. [PDF]

Cell Death Discov
Zhu Q, Gong X, Zhang S, Zhang J, Yan H.
europepmc   +1 more source