Results 111 to 120 of about 1,006,791 (311)

Dissecting the genome-wide evolution and function of R2R3-MYB transcription factor family in Rosa chinensis [PDF]

, 2019
Rosa chinensis, an important ancestor species of Rosa hybrida, the most popular ornamental plant species worldwide, produces flowers with diverse colors and fragrances.
Cheng, Tangren, Han, Yu, Pan, Huitang, Wang, Jia, Yang, Weiru, Yu, Jiayao, Zhang, Qixiang, Zhao, Tao   +7 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Genomic insights into the broad-spectrum antifungal activity of a novel Paenibacillus polymyxa strain X-11

BMC Microbiology
Background The Paenibacillus polymyxa group is potentially useful for regulating plant growth and controlling plant diseases. We previously isolated a novel P. polymyxa strain (X-11) that can promote plant growth.
Wen-zhi Liu, Jin-qing Wang, Peng Li, Feng-chao Yan, Wen-qing Yu, Dan He   +5 more
doaj   +1 more source

The Development of Polyamines throughout Brassica rapa over its Lifecycle [PDF]

, 2014
Polyamines are naturally produced chemicals in plants involved in growth, development and stress response. The primary objective of my study is to create a profile of changes in the entire life of the plant, in every organ at all stages of development ...
Larsen, Jon, Minocha, Subhash C, Sullivan, Matthew Ryan   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Assembly and succession of the phyllosphere microbiome and nutrient-cycling genes during plant community development in a glacier foreland

Environment International
The phyllosphere, particularly the leaf surface of plants, harbors a diverse range of microbiomes that play a vital role in the functioning of terrestrial ecosystems.
Jian Li, Ming-Kang Jin, Lijie Huang, Zhan-Feng Liu, Tao Wang, Rui-Ying Chang, Michiel Op de Beeck, Hans Lambers, Dafeng Hui, Ke-Qing Xiao, Qing-Lin Chen, Jordi Sardans, Josep Peñuelas, Xiao-Ru Yang, Yong-Guan Zhu   +14 more
doaj   +1 more source

PREP-Mt: predictive RNA editor for plant mitochondrial genes

BMC Bioinformatics, 2005
Background In plants, RNA editing is a process that converts specific cytidines to uridines and uridines to cytidines in transcripts from virtually all mitochondrial protein-coding genes.
Mower Jeffrey P
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source