Results 141 to 150 of about 583,785 (310)

SolRgene: an online database to explore disease resistance genes in tuber-bearing Solanum species

, 2011
Background The cultivated potato (Solanum tuberosum L.) is an important food crop, but highly susceptible to many pathogens. The major threat to potato production is the Irish famine pathogen Phytophthora infestans, which causes the devastating late ...
Goverse, A., Berloo, R., van, Jacobsen, E., Jacobs, M.M.J., Hoekstra, R., Vosman, B., Visser, R.G.F., Vleeshouwers, V.G.A.A., Champouret, N., Rietman, H., Huigen, D.J., van Berloo, R., Finkers, H.J., Vissers, M., Bakker, E.H., Budding, D.J., Krenek, P., Pel, M.   +17 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Reference Genes in Plant–Pathogen Interaction: A Bibliometric Analysis

Horticulturae
Plant–pathogen interactions are complex biological processes characterized by dynamic changes in genes expression. In molecular plant pathology research, RT-qPCR has proven to be a valuable tool for investigating plant–pathogen interactions by examining ...
Agata Lizzio, Valerio Battaglia, Ernesto Lahoz, Massimo Reverberi, Milena Petriccione   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Comprehensive analysis of plant rapid alkalization factor (RALF) genes

, 2016
Receptor mediated signal carriers play a critical role in the regulation of plant defense and development. Rapid alkalization factor (RALF) proteins potentially comprise important signaling components which may have a key role in plant biology.
Hussain, Adil, Ali, Asad, Mun, Bong-Gyu, Sharma, Arti, Hong, Jeum Kyu, Loake, Gary John, Imran, Qari Muhammad,, Lee, Sang-Uk, Falak, Noreen, Kim, Jae Young   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Characterization of tomato genes for resistance to Oidium neolycopersici

, 2011
Tomato, Solanum lycopersicum, is a host for Oidium neolycopersici, the cause of powdery mildew (PM). Though cultivated tomatoes are susceptible to PM, resistance is reported in wild Solanum species. By screening wild tomato species, nine loci conferring
Seifi Abdolabad, A.R.
core  

Regulation of Plant Genes with Exogenous RNAs

Exogenous RNA application, also known as spray-induced gene silencing (SIGS), is a new approach in plant biotechnology that utilizes RNA interference (RNAi) to modify plant traits.
Alexandra S. Dubrovina, Andrey R. Suprun, Konstantin V. Kiselev   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plant molecular response to combined drought and nematode stress [PDF]

, 2011
Plants are adapted to respond to precise environmental stress conditions, activating specific molecular and physiological changes in order to minimise damage.
Atkinson, Nicola Jane
core