Results 181 to 190 of about 945,913 (292)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Selection of reliable reference genes in Colletotrichum scovillei during different growth stages, host interactions, and plant extract treatment for qRT-PCR. [PDF]

BMC Plant Biol
Jia GG, Kim SH, Min J, Zamora NV, Montero SS, Yi DK, Kim SY, Oh SK.   +7 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Plant gene conservation [PDF]

Nature, 1986
R. Watkins, N.L. Innes, M.H. Arnold, D. Astley, G.G. Henshaw, B. Tyler, A. H. Bunting, Michael T. Jackson, L.A. Withers, P.M. Mumford, J. Smartt, R.N. Lester, V.H. Heywood, Justine Burley, J. S. Heslop-Harrison, J. G. Hawkes, J. P. Cooper, G. Jenkins, P. Matthews, E. H. Roberts, M.J. Lawrence, J. D. Hayes, N.W. Simmonds, R.J. Giles, Richard Ellis, Brian Ford-Lloyd, P.R. Day, R. D. Smith, J. K. A. Bleasdale, J.A. Callow, Timothy C. Whitmore, E.A. Bell   +31 more
openaire   +2 more sources

Sugar, we're going down: PRC2-mediated epigenetic repression of sucrose metabolism promotes phototrophy during seedling establishment. [PDF]

Plant Cell
Osborne R.
europepmc   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Plant-to-plant horizontal gene transfer [PDF]

Genome Biology, 2003
openaire   +2 more sources

Jumping Genes Cross Plant Species Boundaries.

PLoS Biology, 2006
doaj   +1 more source

Comparative transcriptome profiling and co-expression network analysis reveals important genes regulating maize response to Southern corn rust. [PDF]

BMC Plant Biol
Liu J, Wang K, Wang N, Zhong Y, Zhai X, Jia Y, Chu Z, Miao Q, Su H, Kou M, Duan H, Yan X.   +11 more
europepmc   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source