Results 41 to 50 of about 583,785 (310)
Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte +11 morewiley +1 more sourceSignatures of adaptation to plant parasitism in nematode genomes
, 2015 Each author is, or was, at the time of the work, a paid employee of their affiliated organization. The James Hutton Institute receives funding from the Scottish Government.Charles H. Opperman, Jones, John T., Bird, David McK., Opperman, Charles H., Etienne G. J. Danchin, Taisei Kikuchi, David Mck Bird, John T. Jones, Danchin, Etienne G. J., Kikuchi, Taisei +9 morecore +1 more sourceDeep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand +11 morewiley +1 more sourceThe Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma +3 morewiley +1 more sourceWild soybean (Glycine soja) transcription factor GsWRKY40 plays positive roles in plant salt tolerance
Crop JournalWild soybean (Glycine soja), a relative of cultivated soybean, shows high adaptability to adverse environmental conditions. We identified and characterized a wild soybean transcription factor gene, GsWRKY40, that promotes plant salt stress.Minglong Li, Man Xue, Huiying Ma, Peng Feng, Tong Chen, Xiaohuan Sun, Qiang Li, Xiaodong Ding, Shuzhen Zhang, Jialei Xiao +9 moredoaj +1 more sourceTobacco Transgenic for the Flax Rust Resistance Gene L Expresses Allele-Specific Activation of Defense Responses
Molecular Plant-Microbe Interactions, 2004 Tobacco was transformed with three different alleles (L2, L6, and L10) of the flax rust resistance gene L, a member of the toll interleukin-1 receptor, nucleotide-binding site, leucine-rich repeat (TIR-NBS-LRR) class of plant disease resistance genes. L6 Donna Frost, Heather Way, Paul Howles, Joanne Luck, John Manners, Adrienne Hardham, Jean Finnegan, Jeff Ellis +7 moredoaj +1 more sourceIncreased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure
We Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw +17 morewiley +1 more sourceThe phenotypic expression of QTLs for partial resistance to barley leaf rust during plant development
, 2010 Partial resistance is generally considered to be a durable form of resistance. In barley, Rphq2, Rphq3 and Rphq4 have been identified as consistent quantitative trait loci (QTLs) for partial resistance to the barley leaf rust pathogen Puccinia hordei ...Qi, Xiaoquan, Marcel, Thierry, T., Niks, R.E., Wang, Zhen, Wang, Yajun, Niks, Rients E, Marcel, T.C., Wang, Lijuan +7 morecore +1 more sourceGenomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens [PDF]
, 2009 Background: Pseudomonas fluorescens are common soil bacteria that can improve plant health through nutrient cycling, pathogen antagonism and induction of plant defenses. The genome sequences of strains SBW25 and Pf0-1 were determined and compared to each Mavromatis, K, Zhang, Xue-Xian, Giddens, Stephen R, Preston, Gail, Yaxley, Alice M., Yaxley, A. M., Hothersall, Joanne, Christopher G Knight, Christina D Moon, Jackson, RW, Gregory L Challis, Ana M Cerdeño-Tárraga, Robert W Jackson, Godfrey, Scott A. C., Murphy, Lee, Seeger, K, Spiers, AJ, Levy, SB, Preston, G. M., Godfrey, Scott A C, Rainey, PB, Cerdeño-Tárraga, Ana M, Gehrig, Stefanie M, Jacob G Malone, Gehrig, S. M., Paul B Rainey, Silby, M. W., Challis, GL, Thomson, N. R., Challis, Gregory L, Hothersall, J, Stephens, E, Andrew J Spiers, Zhang, Xue Xian, Elton Stephens, Gehrig, Stefanie M., Thomas, C. M., Nicholas R Thomson, Lee Murphy, Parkhill, J., Gehrig, SM, Spiers, A. J., Godfrey, Scott AC, Squares, Rob, Robinson, Z., Levy, S. B., Malone, Jacob G., Harris, S., Vernikos, Georgios S., Mavromatis, Konstantinos, Giddens, SR, Yaxley, AM, Quail, Michael A., Stephen R Giddens, Silby, Mark W, Quail, M. A., Stephen D Bentley, Brettin, T. S., Brettin, TS, Cerdeño-Tárraga, AM, Vernikos, GS, Challis, G. L., Seeger, K., Julian Parkhill, Saunders, E., Vernikos, G. S., Knight, C. G., Moon, C. D., Quail, Michael A, Georgios S Vernikos, Spiers, Andrew J., Parkhill, Julian, Moon, CD, Kathy Seeger, Preston, Gail M., Mavromatis, K., Joanne Hothersall, Giddens, Stephen R., Murphy, L, Jackson, Robert W, Godfrey, S. A. C., Mark W Silby, Zhang, XX, Knight, Christopher G, Thomas S Brettin, Levy, Stuart B., Thomas, CM, Thomson, NR, Murphy, L., Zhang, X. X., Harris, D., Jackson, Robert W., Murphy, L., Malone, J. G., Quail, MA, Konstantinos Mavromatis, Stuart B Levy, Knight, Christopher G., Silby, MW, Parkhill, J, Moon, Christina D, Rutter, S, Rutter, Simon, Christopher M Thomas, Xue-Xian Zhang, Stephens, E., Bentley, Stephen D, Harris, D., Thomas, Christopher M., Bentley, Stephen D., Zena Robinson, Alice M Yaxley, Stephens, Elton, Vernikos, Georgios S, Knight, C. G., Harris, Simon, David Harris, Robinson, Z., Knight, Christopher G.; id_orcid, Hothersall, J., Bentley, S. D., Scott AC Godfrey, Giddens, S. R., Thomson, Nicholas R, Thomson, Nicholas R., Stefanie M Gehrig, Moon, Christina D., Robinson, Z, Squares, R, Saunders, Elizabeth, Simon Harris, Elizabeth Saunders, Gail M Preston, Godfrey, SA, Bentley, SD, Jackson, R. W., Rainey, Paul B., Rob Squares, Rainey, Paul B, Rainey, P. B., Knight, CG, Cerdeno-Tarraga, A. M., Cerdeño-Tárraga, Ana M., Seeger, Kathy, Harris, S, Preston, Gail M, Rutter, S., Thomas, Christopher; id_orcid, Thomas, Christopher M, Brettin, Thomas S, Thomson, Nicholas Robert, Michael A Quail, Silby, Mark W., Spiers, Andrew J, Squares, R., Saunders, E, Challis, Gregory L., Simon Rutter, Malone, JG, Preston, GM, Harris, D, Robinson, Zena, Saunders, E., Malone, Jacob G, Yaxley, Alice M, Levy, Stuart B, Harris, David, Brettin, Thomas S. +167 morecore +1 more source