Results 251 to 260 of about 759,014 (317)

Transcriptome Analysis Identifies Proteostasis and Cell Survival Pathway Disruption in Peripartum Cardiomyopathy, Leading to Heart Failure. [PDF]

Cells
Choubey P, Montoya-Uribe V, Matter ML.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

SlBL4 is involved in leaf polarity development in tomato. [PDF]

Front Plant Sci
Hu N, Gao X, Chang K, Yu R, Li L, Li J, Li Z, Dai D, Wuriyanghan H, Yan F.   +9 more
europepmc   +1 more source

Differentiation and gene regulation

Current Opinion in Genetics & Development, 1996
openaire   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]

Anim Genet
Akbarin MM, Farjami Z, Murillo CR, González-Fernández VD, Acevedo-Jiménez GE, de María Ávila-De la Vega L, Álvarez HR.   +6 more
europepmc   +1 more source

Sex-Specific Transcriptomic Profiles in Psoriatic Lesions: A Large-Scale Integrative Study. [PDF]

Int J Mol Sci
Stemmer E, Sinberger LA, Lax T, Shrem G, Mor I, Salmon-Divon M.   +5 more
europepmc   +1 more source

Widespread atypical response regulator SecR governs bacterial growth on methylamines through the serine cycle. [PDF]

Commun Biol
Xu J, Li T, Zhou NY.
europepmc   +1 more source