Results 171 to 180 of about 7,597,050 (334)

Species-Specific Differences in Positive and Negative Regulatory Elements in the Renin Gene Enhancer [PDF]

, 1999
Qi Shi, T. Andrew Black, Kenneth W. Gross, Curt D. Sigmund   +3 more
openalex   +1 more source

CLUSTERING SCHIZOPHRENIA GENES BY THEIR TEMPORAL EXPRESSION PATTERNS AIDS FUNCTIONAL INTERPRETATION

, 2022
Dennis van der Meer, Weiqiu Cheng, Jaroslav Rokicki, Sara Fernandez Rodriguez-Cabello, Alexey Shadrin, Friederike Ehrhart, Lars T. Westlye, Ole A. Andreassen, Tobias Kaufmann   +8 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Neurexin facilitates glycosylation of Dystroglycan to sustain muscle architecture and function in Drosophila

Communications Biology
Neurexin, a molecule associated with autism spectrum disorders, is thought to function mainly in neurons. Recently, it was reported that Neurexin is also present in muscle, but the role of Neurexin in muscle is still poorly understood.
Yu Zhao, Junhua Geng, Zhu Meng, Yichen Sun, Mengzhu Ou, Lizhong Xu, Moyi Li, Guangming Gan, Menglong Rui, Junhai Han, Wei Xie   +10 more
doaj   +1 more source

A comparative study of the ability of calcitonin gene‐related peptide and adrenomedullin_13–52 to modulate microvascular but not thermal hyperalgesia responses [PDF]

, 2000
Duc Quyen Chu, ManKin Choy, Paul Foster, Thong Cao, Susan D. Brain   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Differentiation of Porcine TLR4 Gene Expression in Piglets of Different Ages [PDF]

, 2011
ZX Pan, Z. Chen, L. Liu, Yueping Cao, Kaihui Xie, Jie Yang, Xing Huang, Shuqing Wu, W.B. Bao   +8 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

ReninAngiotensinAldosterone System Gene Polymorphisms and Coronary Artery Disease: Detection of Gene-Gene and Gene-Environment Interactions

, 2012
En‐Zhi Jia, Zhenxia Xu, Chang–Yan Guo, Li Li, Yan Gu, Tiebing Zhu, Lian‐Sheng Wang, Kejiang Cao, Wen‐Zhu Ma, Zhijian Yang   +9 more
openalex   +1 more source