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Genes within genes within bacteria
Trends in Biochemical Sciences, 2003Recently, an unusual gene structure has been described in species of the genus Thermus, in which the rpmH (ribosomal protein L34) coding sequence was found to be entirely overlapped by the unusually large rnpA (RNase P protein subunit) sequence. Gene overlap is common in viruses, but has not been seen to this extent in any bacterium.
J Christopher, Ellis, James W, Brown
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Inference: International Review of Science, 2018
A new study, “Russian Doll Genes and Complex Chromosome Rearrangements in Oxytricha trifallax,” casts fresh light on gene nesting and mathematical patterns. Tyler Hampton examines the key findings.
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A new study, “Russian Doll Genes and Complex Chromosome Rearrangements in Oxytricha trifallax,” casts fresh light on gene nesting and mathematical patterns. Tyler Hampton examines the key findings.
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Songs of Genes, by Genes, for Genes
Leonardo, 2012The authors have defined a new concept of “base_position” and translated the protein-coding sequence to a sequence consisting of 12 base_positions. The authors developed a new algorithm for translating the base_position sequence to a melody with a range of at most a twelfth and without leaps larger than an octave, which should be turned upside-down by
Dongya Ge, Yixue Li
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Analysis of Gene‐Gene Interactions
Current Protocols in Human Genetics, 2003AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
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Tandem genes and clustered genes
Journal of Theoretical Biology, 1995Two patterns of gene repetition are described: tandem arraying and clustering. Tandemly arrayed genes reside within segments of DNA that are repeated head-to-tail a number of times. Clustered genes are linked but irregularly spaced, are often mutually inverted in an unpredictable pattern and are connected by non-conserved DNA.
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Better Gene Expression by (-)Gene than by (+)Gene in Phage Gene Delivery Systems
Biotechnology Progress, 2006In recent years, capsid-modified filamentous bacteriophage has become a potential vector for gene delivery into mammalian cells. However, little was known about how the carried gene in the single-stranded genome expressed in mammalian cells. To explore whether the orientation of the carried gene affects its expression in the cells, we prepared EGF ...
Yun, Liang +6 more
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Gene Duplication and Gene Loading
2014During the early evolution of life, gene duplication, the production of two copies of a DNA sequence, allowed the rapid diversification of enzymatically catalyzed reactions and an increase in genome size, providing also material for the invention of new enzymatic properties and complex regulatory and developmental patterns. A duplication may involve (i)
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