Results 71 to 80 of about 11,860,410 (381)
BMC Medical Research Methodology, 2022 Background As the cost of RNA-sequencing decreases, complex study designs, including paired, longitudinal, and other correlated designs, become increasingly feasible.
Elizabeth A. Wynn +3 more
doaj +1 more source
Phase-noise induced limitations on cooling and coherent evolution in opto-mechanical systems
, 2009 We present a detailed theoretical discussion of the effects of ubiquitous laser noise on cooling and the coherent dynamics in opto-mechanical systems. Phase fluctuations of the driving laser induce modulations of the linearized opto-mechanical coupling ...
C. Genes +4 more
core +1 more source
Pancancer survival analysis of cancer hallmark genes
Scientific Reports, 2020 Cancer hallmark genes are responsible for the most essential phenotypic characteristics of malignant transformation and progression. In this study, our aim was to estimate the prognostic effect of the established cancer hallmark genes in multiple ...
Á. Nagy, G. Munkácsy, Balázs Győrffy
semanticscholar +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Molecular Systems Biology, 2009 The molecular complexity of mammalian proteomes demands new methods for mapping the organization of multiprotein complexes. Here, we combine mouse genetics and proteomics to characterize synapse protein complexes and interaction networks.
Esperanza Fernández +9 more
doaj +1 more source
A new AAV tool for highly preferentially targeting hippocampal CA2
Molecular Brain, 2023 Mice hippocampus contains three prominent subregions, CA1, CA3 and DG and is well regarded as an essential multiple task processor for learning, memory and cognition based on tremendous studies on these three subregions.
Siqi Peng +8 more
doaj +1 more source
Partial optomechanical refrigeration via multi-mode cold-damping feedback
, 2019 We provide a fully analytical treatment for the partial refrigeration of the thermal motion of a quantum mechanical resonator under the action of feedback.
Genes, C., Sommer, C.
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Gene–gene and gene–environment interactions in ulcerative colitis [PDF]
Human Genetics, 2013 Genome-wide association studies (GWAS) have identified at least 133 ulcerative colitis (UC) associated loci. The role of genetic factors in clinical practice is not clearly defined. The relevance of genetic variants to disease pathogenesis is still uncertain because of not characterized gene-gene and gene-environment interactions.
M. Ilyas Kamboh +8 more
openaire +3 more sources
Genome-Wide Analysis of Glycine soja Response Regulator GsRR Genes Under Alkali and Salt Stresses
Frontiers in Plant Science, 2018 Soil salt-alkalization is a dramatic challenging factor for plant growth. Wild soybean (Glycine soja) exhibits a favorable trait of superior tolerance to salt-alkali stress, and recent discoveries show that response regulator family genes are involved in
Chao Chen +8 more
doaj +1 more source