Results 71 to 80 of about 7,597,050 (334)
Gene–gene and gene–environment interactions in ulcerative colitis [PDF]
Human Genetics, 2013 Genome-wide association studies (GWAS) have identified at least 133 ulcerative colitis (UC) associated loci. The role of genetic factors in clinical practice is not clearly defined. The relevance of genetic variants to disease pathogenesis is still uncertain because of not characterized gene-gene and gene-environment interactions.
Ming-Hsi, Wang +7 more
openaire +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Cavity-assisted squeezing of a mechanical oscillator
, 2009 We investigate the creation of squeezed states of a vibrating membrane or a movable mirror in an opto-mechanical system. An optical cavity is driven by squeezed light and couples via radiation pressure to the membrane/mirror, effectively providing a ...
Genes, C. +5 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Blood PressureObjective This study aimed to investigate the relationship between exaggerated hypertensive response to exercise (EHRE), mobile phone screen time and daily physical activity levels, with a focus on potential lifestyle-related factors that contribute to ...
Muhammet Geneş, Cem Barçin
doaj +1 more source
Hybrid cavity mechanics with doped systems
, 2014 We investigate the dynamics of a mechanical resonator in which is embedded an ensemble of two-level systems interacting with an optical cavity field. We show that this hybrid approach to optomechanics allows for enhanced effective interactions between ...
Dantan, Aurelien +3 more
core +1 more source
Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum. [PDF]
, 2015 BackgroundPlasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging.
Bunnik, Evelien M +5 more
core +2 more sources
Gene-Gene Cooperativity in Small Networks [PDF]
Biophysical Journal, 2009 22 pages, 10 ...
Walczak, Aleksandra M. +1 more
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
LifeBackground: Despite ongoing advancements in healthcare, acute coronary syndromes (ACS) remain a leading cause of morbidity and mortality. The 2023 European Society of Cardiology (ESC) guidelines have introduced significant improvements in ACS management.
Muhammet Geneş, Murat Çelik
doaj +1 more source