Results 141 to 150 of about 47,618 (305)

An ontological morphological phylogenetic framework for living and extinct ray‐finned fishes (Actinopterygii)

open access: yesThe Anatomical Record, EarlyView.
Abstract The ray‐finned fishes include one out of every two species of living vertebrates on Earth and have an abundant fossil record stretching 380 million years into the past. The division of systematic knowledge of ray‐finned fishes between paleontologists working on extinct animals and neontologists studying extant species has obscured the ...
Jack Stack
wiley   +1 more source

Hypothetical LOC Genes as Biomarkers of Spaceflight Adaptation: A Comparative Study from ISS, Suborbital, and Earth-Based Experiments

open access: yes
Abstract Microgravity constitutes one of the most profound environmental stressors encountered by humans during spaceflight, capable of altering fundamental cellular processes and gene regulatory networks. While the effects of spaceflight on well-characterized protein-coding genes have been widely documented, little is known about the ...
Özge Demir   +6 more
openaire   +1 more source

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

open access: yesAnimal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao   +11 more
wiley   +1 more source

Metabolic stress in space: ROS-induced mutations in mice hint at a new path to cancer

open access: yesRedox Biology
Long-duration spaceflight beyond Earth's magnetosphere poses serious health risks, including muscle atrophy, bone loss, liver and kidney damage, and the Spaceflight-Associated Neuro-ocular Syndrome (SANS).
Viktor Stolc   +5 more
doaj   +1 more source

Development of usable grid services for the biomedical community [PDF]

open access: yes, 2006
The BRIDGES project was funded by the UK Department of Trade and Industry to directly address the needs of the cardiovascular research scientists investigating the genetic causes of hypertension as part of the Wellcome Trust funded (£4.34M ...
Sinnott, R.O.
core  

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

open access: yesAnimal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou   +4 more
wiley   +1 more source

Operationalising global education in teacher education and training: A model for contextualising terminology

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Despite a growing international consensus that students need to be provided with the type of education that effectively prepares them to engage in and contribute to their globalised world, and that teachers need to be appropriately trained to facilitate this teaching and learning, ‘global education’ continues to be hindered by a lack of ...
Sarah‐Louise Jones   +2 more
wiley   +1 more source

The experiments Gene and Ageing performed in the International Space Station (ISS) during the Spanish Soyuz Mission

open access: yes, 2004
Supported by Spanish Government Grants ESP2002-11913-E and ESP2003-09475-C01-
Marco, Roberto   +8 more
openaire   +1 more source

Harnessing Cellular Feeling: Epigenetic to Mechanical Memory as a Framework for Stem Cell Manufacturing

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Stem cell‐based therapies hold transformative potential for regenerative medicine, yet their progress is constrained by persistent variability in manufacturing and clinical performance. Conventional frameworks such as Quality by Design (QbD), though effective for drugs and biologics, struggle to accommodate the dynamic nature of living cell ...
Mee‐Hae Kim, Masahiro Kino‐oka
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

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