Results 151 to 160 of about 14,810 (217)

Single-nucleotide variants as potential prognostic biomarkers in newly diagnosed multiple myeloma patients. [PDF]

Hematol Transfus Cell Ther
Garrido D, Ledesma M, Stella F, Galvano C, Lopresti S, Riva E, Fundia A, Slavutsky I.   +7 more
europepmc   +1 more source

Prognostic Significance of Peripheral Blood Neutrophil‐To‐Lymphocyte Ratio (NLR), Monocyte‐To‐Lymphocyte Ratio (MLR), and Platelet‐To‐Lymphocyte Ratio (PLR) in Patients With Multiple Myeloma: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the prognostic significance of systemic inflammatory markers in Multiple Myeloma (MM). The left panel depicts the immunosuppressive tumor microenvironment, where abundant neutrophils and M2 macrophages promote MM cell survival while lymphocytes are depleted.
Lihong Zhang, Bing Ma, Jingyu Zhang
wiley   +1 more source

Emerging co-occurrence of mcr-10 and broad-spectrum β-lactamase genes in Enterobacterales from surface waters in Brazil. [PDF]

Environ Monit Assess
da Silva Rosa R, Furlan JPR, Dos Santos LDR, Ramos MS, Savazzi EA, Stehling EG.   +5 more
europepmc   +1 more source

When Being Social Is Costly: Empathy's Role for Risk States, Acute Symptoms, and Cumulative Disease Severity of Depression

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Patients with major depressive disorder (MDD) frequently report burdensome interpersonal difficulties and altered empathy and perspective‐taking. Previous findings on binary comparisons between patients and healthy controls are limited in their clinical translation as they neglect dissociable risk and disease states.
Dahna Choi, Paula L. Usemann, Katharina Förster, Roland Zahn, Vincent Hammes, Frederike Stein, Florian Thomas‐Odenthal, Lea Teutenberg, Kira Flinkenflügel, Julia Hubbert, Christoph Jurischka, Judith Krieger, Elisabeth J. Leehr, Susanne Meinert, Tim Hahn, Jonathan Repple, Nils Opel, Hamidreza Jamalabadi, Andreas Jansen, Benjamin Straube, Igor Nenadić, Udo Dannlowski, Tilo Kircher, Nina Alexander, Philipp Kanske   +24 more
wiley   +1 more source

Infantile Spasms (West Syndrome): Integrating Genetic, Neurotrophic, and Hormonal Mechanisms Toward Precision Therapy. [PDF]

Medicina (Kaunas)
Abdygalyk B, Rabandiyarov M, Lepessova M, Koshkimbayeva G, Zharkinbekova N, Tekebayeva L, Zhailganov A, Issabekova A, Myrzaliyeva B, Tulendiyeva A, Kurmantay A, Turmanbetova A, Yerkenova S.   +12 more
europepmc   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz, Leyre Gambra, Samuele Cortese, Pablo Lizoain, Diana Rodriguez‐Romero, Ursula Paiva, Carmen Gándara, Sara Magallón, Gonzalo Arrondo   +8 more
wiley   +1 more source

Defining High-Risk Disease Biology in Multiple Myeloma: A Narrative Review. [PDF]

Blood Lymphat Cancer
Aljumaa M, Hamam Refai H, Chawla Y, Gonsalves WI.   +3 more
europepmc   +1 more source

Looking at Soil as It Is: Evolution of Microscopic Soil Characterization From Kubiëna to Artificial Intelligence

Journal of Plant Nutrition and Soil Science, EarlyView.
We provide a historic overview of microscopic soil structure characterization from its founding father, Walter Kubiëna, to several technical revolutions like automation, digitalization, and artificial intelligence. In addition to technical advancements, we explore how concepts and research questions have evolved in time.
Steffen Schlüter, Maik Geers‐Lucas, Peter Kühn, Hans‐Jörg Vogel   +3 more
wiley   +1 more source

Reduced Mechanical Tactile Stimulation Under Space Microgravity Affects Synaptic Signaling and Contributes to Neuromuscular Aging in Caenorhabditis elegans. [PDF]

FASEB J
Higashitani A, Moon JH, Hwang JI, Higashitani N, Hashizume T, Abu AA, Ooizumi K, Sazuka I, Hashizume Y, Umehara M, Alcantara AV, Kim BS, Etheridge T, Szewczyk NJ, Abe T, Lee JI, Higashibata A.   +16 more
europepmc   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source