Results 91 to 100 of about 896,271 (269)

Real-World Treatment Patterns, Sequencing, and Outcomes in Patients with Locally Advanced or Metastatic Urothelial Carcinoma Receiving Avelumab First-Line Maintenance in the United States

Current Oncology
For patients with locally advanced/metastatic urothelial carcinoma (la/mUC), first-line (1L) treatment with platinum-based chemotherapy (PBC) followed by avelumab 1L maintenance (1LM) is a recommended therapy per treatment guidelines in patients without ...
Helen H. Moon, Mairead Kearney, Seyed Hamidreza Mahmoudpour, Chiemeka Ike, Valerie Morris, Andrew Rava, Sonia Kim, Haiyan Sun, Marley Boyd, Gabriel Gomez Rey   +9 more
doaj   +1 more source

Functional Segregation of Epileptogenicity within the Human Amygdala

Annals of Neurology, EarlyView.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys, Julia Makhalova, Samuel Medina Villalon, Maria Fratello, Hugo Dary, Stanislas Lagarde, Francesca Pizzo, Agnès Trébuchon, Maxime Guye, Jean‐Philippe Ranjeva, Romain Carron, Didier Scavarda, Christian‐George Bénar, Bernard Giusiano, Fabrice Bartolomei   +14 more
wiley   +1 more source

Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis

Frontiers in Immunology, 2017
A diverse antibody repertoire is primarily generated by the rearrangement of V, D, and J genes and subsequent somatic hypermutation (SHM). Class-switch recombination (CSR) produces various isotypes and subclasses with different functional properties ...
Kazutaka Kitaura, Hiroshi Yamashita, Hitomi Ayabe, Tadasu Shini, Tadasu Shini, Takaji Matsutani, Ryuji Suzuki, Ryuji Suzuki   +7 more
doaj   +1 more source

Geometry of Majorana neutrino and new symmetries

, 2006
Experimental observation of Majorana fermion matter gives a new impetus to the understanding of the Lorentz symmetry and its extension, the geometrical properties of the ambient space-time structure, matter--antimatter symmetry and some new ways to ...
Volkov, G. G.
core  

Comparison of Fracture Resistance and Quality of Lateral Condensation Obturation in Traditional and Conservative Access Cavity Preparation: An In Vitro Study [PDF]

Dental Journal of Advance Studies
Introduction: Access cavity preparation is indeed a pivotal step in successful endodontic treatment. It ensures efficient removal of diseased or infected tissue, facilitates thorough cleaning, and enables effective shaping and sealing of the root canal ...
Gurkiran Kaur, Purshottam Jasuja, Shveta Munjal, Heena Khurana, Ekta Gakhar, Suman Sharma   +5 more
doaj   +1 more source

NEXT-GENERATION SEQUENCING APPLIED TO THE IDENTIFICATION OF CMV ANTIVIRAL RESISTANCE MUTATIONS: DEVELOPMENT AND VALIDATION OF AN ASSAY FOR CLINICAL USE

Brazilian Journal of Infectious Diseases
Introduction/Objective: Cytomegalovirus (CMV), a member of the Herpesviridae family, is widely distributed globally and usually causes asymptomatic infection or self-limited symptoms, followed by latency for an indeterminate time in immunocompetent ...
Luciana Alves de Fatima, Joice do Prado Silva, Bruno Spinetti Moda, Deyvid Emanuel Amgarten, Raquel Riyuzo de Almeida Franco, Nair Hideko Muto, Fernanda de Mello Malta, Erick Gustavo Dorlass, Carolina dos Santos Lazari, Celso Granato, André Mario Doi, João Renato Rebello Pinho, Ana Maria Fraga   +12 more
doaj   +1 more source

Digital Genesis: Computers, Evolution and Artificial Life [PDF]

, 2015
The application of evolution in the digital realm, with the goal of creating artificial intelligence and artificial life, has a history as long as that of the digital computer itself.
Dorin, Alan, Korb, Kevin, Taylor, Tim
core  

CHARACTERISTICS OF CHAIN OF PEA VARIETIES FOR VEGQ ETABLE CANNING

Овощи России, 2015
The characteristics of seven pea varieties of different groups of ripening are described. These cultivars provide the sustainable row material input in canning factories of Krasnodar region. In bogharic agriculture it takes 24,26 days.
N. A. Samarin, S. N. Samarin
doaj   +1 more source

Genesis of the 1000-Foot Arecibo Dish [PDF]

, 2009
The giant radar/radio astronomy dish near Arecibo, Puerto Rico, was conceived by William E. Gordon in early 1958 as a back-scattering radar system to measure the density and temperature of the Earth’s ionosphere up to a few thousand kilometers.
Cohen, Marshall H.
core  

Mechanism of Hydrogen Sulfide Generation and Prevention Strategies in Oil and Gas Fields: A Case Study of the Sickle Bay Operation Area

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To address the persistent exceedance of hydrogen sulfide (H2S) concentrations and the limited effectiveness of existing treatments in the Sickle Bay oil production area, this study deeply analyzes the mechanism of H2S generation in the Sickle Bay oil production area and proposes targeted prevention and control strategies. The results show that
Bo Lei, Yao‐long Li, Bao‐ping Bai, Xiang‐de Zhang, Guan‐tao Shi, Yong‐long Xie, Chen‐xiao Hou, Cong‐Yu Ke   +7 more
wiley   +1 more source