Results 51 to 60 of about 963,673 (322)

A Score-Based Rapid Screening and Network Visualization Method Based on Bioactive Ingredient-Induced Variations in Skin Cell Gene Expression

Scientia Pharmaceutica
Bioactive ingredients are compounds, typically derived from natural sources, that provide specific health benefits or perform certain beneficial functions. Although they can play a role in maintaining good health, their effects can vary widely based on a
Mio Ogawa, Charles W. Crawford, Ayumu Ishigaki, Iri Sato-Baran, David D. Ordinario, Tadayoshi Miyashita   +5 more
doaj   +1 more source

Administrative penalties: Impact and alternatives

Journal of Economic and Financial Sciences, 2011
Administrative penalties are imposed in South Africa for a specified set of prohibited practices. These are typically the most egregious anti-competitive acts, and therefore the main purpose of administrative penalties is to act as a deterrent, both to ...
Jason Aproskie, Sha’ista Goga
doaj   +1 more source

In Search of the Solar Wind Nitrogen Isotope Composition: Analysis of a Gold Plate from the Genesis Spacecraft Concentrator [PDF]

, 2008
We report N isotope analysis of a gold plate from the Genesis spacecraft concentrator.
Allton, J. H., Burnard, P. G., Burnett, D. S., Franchi, I. A., Heber, V. S., Marty, B., Sestak, S., Wieler, R., Wiens, R. C., Zimmermann, L.   +9 more
core  

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Technological Claustrophobia [PDF]

, 2008
Tim O'Riley discusses the genesis of his project to examine how technology can be used to construct a speculative model of a physical and spatial ...
O'Riley, Tim
core  

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Evaluation of the usefulness of saliva for mosaic loss of chromosome Y analysis

Scientific Reports, 2021
Mosaic loss of chromosome Y (mLOY) in leukocytes has attracted much attention as an emerging biomarker of aging and aging-related diseases. We evaluated the usefulness of saliva for mLOY analysis and showed that saliva-derived mLOY is significantly ...
Tsuyoshi Hachiya, Takuro Kobayashi, Wataru Tsutae, Pamela Hui Peng Gan, Iri Sato Baran, Shigeo Horie   +5 more
doaj   +1 more source

Context for Confusion: Understanding Babel in the Book of Beginnings [PDF]

, 2018
The meaning of the Tower of Babel episode in Genesis 11 proves to be continually elusive for both biblical scholars and pastors. While the results of this momentous event in world history seem obvious, owing to the racial and linguistic diversity present
Osselaer, Douglas R
core   +1 more source

Modeling a Grid-Connected PV/Battery Microgrid System with MPPT Controller

, 2017
This paper focuses on performance analyzing and dynamic modeling of the current grid-tied fixed array 6.84kW solar photovoltaic system located at Florida Atlantic University (FAU).
Alvarez, Genesis, Moradi, Hadis, Smith, Mathew, Zilouchian, Ali   +3 more
core   +1 more source

Did the Universe Have a Chance? [PDF]

, 2018
In a world awash in statistical patterns, should we conclude that the universe’s evolution or genesis is somehow subject to chance? I draw attention to alternatives that must be acknowledged if we are to have an adequate assessment of what chance the ...
McCoy, C. D.
core   +4 more sources