Results 91 to 100 of about 7,786,025 (339)

New bearings in pharmacotherapeutic strategies: Pharmacogenetics and gene therapy [PDF]

open access: yesVojnosanitetski Pregled, 2007
Grbović Leposava   +4 more
doaj   +1 more source

In Vivo Models of Cardiovascular Disease: Drosophila melanogaster as a Genetic Model of Congenital Heart Disease

open access: yesBiomedicines
Drosophila melanogaster (D. melanogaster) has been widely used in biology, including classical genetics, for almost a century. With the entire D. melanogaster genome sequenced and the existence of transgenic and mutant individuals, the species offers ...
Theodora M Stougiannou   +3 more
doaj   +1 more source

The Role of the CGIAR in Plant Genetic Resources: Towards a System-Wide Strategy [PDF]

open access: yes, 1993
A revision by IBPGR of a paper considered at TAC 57 and in a joint meeting with center directors at TAC 59. See the document titled Changing Responsibilities and Roles for Plant Genetic Resources within the CGIAR System (October 1992) and its attachments.
International Board for Plant Genetic Resources
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Diagnosis and treatment of isolated autosomal recessive woolly hair/hypotrichosis

open access: yesFrontiers in Medicine
Isolated autosomal recessive woolly hair/hypotrichosis (ARWH, OMIM:278150) is a rare congenital disorder marked by sparse, tightly curled “woolly” hair.
Ying Xie   +13 more
doaj   +1 more source

Genetic modification and genetic determinism.

open access: yesPhilosophy, ethics, and humanities in medicine : PEHM, 2006
In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism.
Vorhaus Daniel B, Resnik David B
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Antipsychotic-induced weight gain: The role of the genetics

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Parallel to the increasingly common use of second generation antipsychotics, some metabolic side effects started to draw attention, one of which is weight gain. Weight gain is an important problem both for general health and psychiatric morbidity.
Kemal Yazıcı, Aylin Yazıcı
doaj  

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