Genetic evidence for archaic admixture in Africa [PDF]
Proceedings of the National Academy of Sciences, 2011 A long-debated question concerns the fate of archaic forms of the genus Homo : did they go extinct without interbreeding with anatomically modern humans, or are their genes present in contemporary populations? This question is typically focused on the genetic contribution of archaic forms outside of Africa.
Michael F, Hammer +4 more
openaire +2 more sources
Evaluation of group genetic ancestry of populations from Philadelphia and Dakar in the context of sex-biased admixture in the Americas. [PDF]
PLoS ONE, 2009 Population history can be reflected in group genetic ancestry, where genomic variation captured by the mitochondrial DNA (mtDNA) and non-recombining portion of the Y chromosome (NRY) can separate female- and male-specific admixture processes.
Klara Stefflova +7 more
doaj +1 more source
Genetic Landscape of Eurasia and “Admixture” in Uyghurs [PDF]
The American Journal of Human Genetics, 2009 To the Editor: In the papers1,2 by Xu and Jin, the genetic structure of Uyghurs was described by 8150 ancestry-informative markers (AIMs). These markers estimated the admixture rate of the Uyghur population to be around 50% East Asian ancestry by comparing Uyghurs to East Asians and Europeans.
Li, Hui +3 more
openaire +2 more sources
CoAIMs: a cost-effective panel of ancestry informative markers for determining continental origins. [PDF]
PLoS ONE, 2010 Genetic ancestry is known to impact outcomes of genotype-phenotype studies that are designed to identify risk for common diseases in human populations.
Eric R Londin +8 more
doaj +1 more source
Admixture Correction in the Outgroup-f3 Statistic [PDF]
, 2018 Genetic inheritance can be studied within a purely genetic scope. However, this eliminates part of the picture. The field of genetics is often thought of as a natural science with little in common with fields of social science. However, in human genetics
Tunga, Nita
core +1 more source
PLoS ONE, 2012 Recently admixed populations offer unique opportunities for studying human history and for elucidating the genetic basis of complex traits that differ in prevalence between human populations. Historical records, classical protein markers, and preliminary
Sandra Beleza +7 more
doaj +1 more source
Fast individual ancestry inference from DNA sequence data leveraging allele frequencies for multiple populations. [PDF]
, 2015 BackgroundEstimation of individual ancestry from genetic data is useful for the analysis of disease association studies, understanding human population history and interpreting personal genomic variation. New, computationally efficient methods are needed
Bansal, Vikas, Libiger, Ondrej
core +2 more sources
Calculating expected DNA remnants from ancient founding events in human population genetics
BMC Genetics, 2008 Background Recent advancements in sequencing and computational technologies have led to rapid generation and analysis of high quality genetic data.
Stacey Andrew +2 more
doaj +1 more source
Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates. [PDF]
, 2020 Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP)
Aldana, Ileana +37 more
core +3 more sources
Genetic admixture drives climate adaptation in the bank vole. [PDF]
Commun BiolAbstractGenetic admixture introduces new variants at relatively high frequencies, potentially aiding rapid responses to environmental changes. Here, we evaluate its role in adaptive variation related to climatic conditions in bank voles (Clethrionomys glareolus) in Britain, using whole-genome data.
Horníková M +5 more
europepmc +4 more sources