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Overview of Admixture Mapping [PDF]
Current Protocols in Human Genetics, 2013 AbstractAdmixture mapping is a powerful method of gene mapping for diseases or traits that show differential risk by ancestry. Admixture mapping has been applied most often to Americans who trace ancestry to various combinations of Native Americans, Europeans, and West Africans.
Daniel Shriner
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PLOS Genetics, 2021 Throughout human history, large-scale migrations have facilitated the formation of populations with ancestry from multiple previously separated populations. This process leads to subsequent shuffling of genetic ancestry through recombination, producing variation in ancestry between populations, among individuals in a population, and along the genome ...
Katharine L. Korunes, Amy Goldberg
openaire +5 more sources
The Lengths of Admixture Tracts [PDF]
Genetics, 2014 Abstract The distribution of admixture tract lengths has received considerable attention, in part because it can be used to infer the timing of past gene flow events between populations. It is commonly assumed that these lengths can be modeled as independently and identically distributed (iid) exponential random variables.
Rasmus Nielsen, , Nielsen Rasmus
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Inference on admixture fractions in a mechanistic model of recurrent admixture [PDF]
Theoretical Population Biology, 2018 Signatures of recent historical admixture are ubiquitous in human populations. We present a mechanistic model of admixture with two source populations, encompassing recurrent admixture periods and study the distribution of admixture fractions for finite but arbitrary genome size.
Paul Verdú
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Platinum Accumulation and Cancer-Related Fatigue, Correlation With IL-8, TNF-α and Hemocytes
Frontiers in Pharmacology, 2021 Platinum-based chemotherapy drugs cause platinum accumulation and result in cancer-related fatigue (CRF), which is related to immune response through still ambiguous mechanisms.
Yuling Zhang +5 more
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Results in Physics, 2021 The purpose is to explore the positive role of PDCA (Plan, Do, Check, Act) cycle theory in the hospital information management system to avoid intravenous drug bacterial infection of nursing staff based 360-degree quantitative evaluation model.
Lina Jiang +4 more
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Biomolecules, 2022 (1) Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity. The epithelial-mesenchymal transition (EMT) is one of the inducers of cancer metastasis and migration.
Yang Liu +5 more
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BMC Research Notes, 2022 Objective As low-dose atropine eye-drops for myopia progression control prepared in-house by diluting the commercial 0.1% atropine eye-drop with sterile water or normal saline has been a common practice whereas atropine injection is readily available and
Nuthida Wongwirawat +3 more
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Evolutionary Genetics and Admixture in African Populations
Genome Biology and Evolution, 2023 As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity and substantial population structure. Importantly, African genomes are heterogeneous: They contain mixtures of multiple ancestries, each of which have ...
Aaron Pfennig +3 more
semanticscholar +1 more source
Frontiers in Ecology and Evolution, 2021 Gene flow among crops and their wild relatives is an active study area in evolutionary biology and horticulture, because genetic exchange between them may impact their evolutionary trajectories and increase the genetic variation of the cultivated ...
Carmina Martínez-González +11 more
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