Results 21 to 30 of about 138,461 (306)
Assessing the performance of qpAdm: a statistical tool for studying population admixture
bioRxiv, 2020 qpAdm is a statistical tool for studying the ancestry of populations with histories that involve admixture between two or more source populations. Using qpAdm, it is possible to identify plausible models of admixture that fit the population history of a ...
Éadaoin Harney +3 more
semanticscholar +1 more source
eLife, 2020 People in the Americas represent a diverse continuum of populations with varying degrees of admixture among African, European, and Amerindigenous ancestries.
Melissa L Spear +6 more
doaj +1 more source
Evolutionary Applications, 2021 Due to their isolated and often fragmented nature, range margin populations are especially vulnerable to rapid environmental change. To maintain genetic diversity and adaptive potential, gene flow from disjunct populations might therefore be crucial to ...
Binia De Cahsan +6 more
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An efficient method to identify, date, and describe admixture events using haplotype information
bioRxiv, 2021 We present fastGLOBETROTTER, an efficient new haplotype-based technique to identify, date and describe admixture events using genome-wide autosomal data. With simulations, we demonstrate how fastGLOBETROTTER reduces computation time by 4-20 fold relative
Pongsakorn Wangkumhang +2 more
semanticscholar +1 more source
Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data
Genetics, 2018 Meisner and Albrechtsen present two methods for inferring population structure and admixture proportions in low depth next-generation sequencing (NGS).
J. Meisner, A. Albrechtsen
semanticscholar +1 more source
Enhancements to the ADMIXTURE algorithm for individual ancestry estimation
BMC Bioinformatics, 2011 BackgroundThe estimation of individual ancestry from genetic data has become essential to applied population genetics and genetic epidemiology. Software programs for calculating ancestry estimates have become essential tools in the geneticist's analytic ...
David H. Alexander, K. Lange
semanticscholar +1 more source
Advancing admixture graph estimation via maximum likelihood network orientation
bioRxiv, 2021 Motivation Admixture, the interbreeding between previously distinct populations, is a pervasive force in evolution. The evolutionary history of populations in the presence of admixture can be modeled by augmenting phylogenetic trees with additional nodes
Erin K. Molloy +2 more
semanticscholar +1 more source
Evaluating the Accuracy of Imputation Methods in a Five-Way Admixed Population
Frontiers in Genetics, 2019 Genotype imputation is a powerful tool for increasing statistical power in an association analysis. Meta-analysis of multiple study datasets also requires a substantial overlap of SNPs for a successful association analysis, which can be achieved by ...
Haiko Schurz +9 more
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A tutorial on how not to over-interpret STRUCTURE and ADMIXTURE bar plots
Nature Communications, 2018 Genetic clustering algorithms, implemented in programs such as STRUCTURE and ADMIXTURE, have been used extensively in the characterisation of individuals and populations based on genetic data.
D. Lawson, L. van Dorp, D. Falush
semanticscholar +1 more source
Influence of Admixture on Phenotypes
Current Protocols, 2023 AbstractIndividuals of European descent have historically been the focus of genetic studies and possess relatively homogenous genomes. As a result, analytical methods have been developed and optimized with such genomes in mind. African‐descent and Latino individuals generally possess genomes of greater architectural complexity due to mosaic genomic ...
Steven W. Brugger, Mary F. Davis
openaire +2 more sources