Results 31 to 40 of about 90,459 (309)

Genetic Stratigraphy of Key Demographic Events in Arabia [PDF]

open access: yes, 2015
The issue of admixture in human populations is normally addressed by genome-wide (GW) studies, and several approaches have been developed to date admixture events [1,2,3,4,5].
Alison Machado (698496)   +60 more
core   +1 more source

Time since admixture.

open access: yes, 2021
Estimated generations since admixture under a three-way admixture model: a founding mexicana population receives a pulse of parviglumis admixture and then a second pulse of maize admixture (possibly resulting in majority maize ancestry).
Anne Lorant (3930761)   +5 more
core   +1 more source

Evaluating the Accuracy of Imputation Methods in a Five-Way Admixed Population

open access: yesFrontiers in Genetics, 2019
Genotype imputation is a powerful tool for increasing statistical power in an association analysis. Meta-analysis of multiple study datasets also requires a substantial overlap of SNPs for a successful association analysis, which can be achieved by ...
Haiko Schurz   +9 more
doaj   +1 more source

Source code: Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

open access: yes, 2020
This version of the source code reflects analyses included in the peer-reviewed manuscript "Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx" provisionally accepted for publication.
Nicole R. Gay
core   +1 more source

Admixture patterns and genetic differentiation in negrito groups from West Malaysia estimated from genome-wide SNP data [PDF]

open access: yes, 2013
Southeast Asia houses various culturally and linguistically diverse ethnic groups. In Malaysia, where the Malay, Chinese, and Indian ethnic groups form the majority, there exist minority groups such as the "negritos" who are believed to be descendants of
Maude E., Phipps   +2 more
core   +1 more source

Influence of Admixture on Phenotypes

open access: yesCurrent Protocols, 2023
AbstractIndividuals of European descent have historically been the focus of genetic studies and possess relatively homogenous genomes. As a result, analytical methods have been developed and optimized with such genomes in mind. African‐descent and Latino individuals generally possess genomes of greater architectural complexity due to mosaic genomic ...
Steven W. Brugger, Mary F. Davis
openaire   +2 more sources

Human genetic admixture

open access: yesPLOS Genetics, 2021
Throughout human history, large-scale migrations have facilitated the formation of populations with ancestry from multiple previously separated populations. This process leads to subsequent shuffling of genetic ancestry through recombination, producing variation in ancestry between populations, among individuals in a population, and along the genome ...
Katharine L. Korunes, Amy Goldberg
openaire   +4 more sources

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

open access: yesFrontiers in Pharmacology, 2017
Existing algorithms account for ~50% of observed variance in warfarin dose requirements after including common polymorphisms. However, they do not perform as well in populations other than Caucasians, in part because some ethno-specific genetic variants ...
Karla Claudio-Campos   +11 more
doaj   +1 more source

Candidate‐species delimitation in Desmognathus salamanders reveals gene flow across lineage boundaries, confounding phylogenetic estimation and clarifying hybrid zones

open access: yesEcology and Evolution, 2022
Dusky Salamanders (genus Desmognathus) currently comprise only 22 described, extant species. However, recent mitochondrial and nuclear estimates indicate the presence of up to 49 candidate species based on ecogeographic sampling.
Robert Alexander Pyron   +4 more
doaj   +1 more source

Heterogeneity of Genetic Admixture Determines SLE Susceptibility in Mexican

open access: yesFrontiers in Genetics, 2021
Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disorder for which Major Histocompatibility Complex (MHC) genes are well identified as risk factors.
Susana Hernández-Doño   +12 more
doaj   +1 more source

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