Results 141 to 150 of about 4,042,191 (370)
Two rare mutations in homozygosity synergize to silence TREX1 in Aicardi-Goutières syndrome
Frontiers in ImmunologyBackgroundAicardi-Goutières syndrome (AGS) is a rare monogenic type I interferonopathy characterized by dysregulated inflammation and tissue damage that primarily affects the central nervous system.
Tamar Rubin +15 more
doaj +1 more source
A Model of Genome Size Evolution for Prokaryotes in Stable and Fluctuating Environments [PDF]
, 2015 Temporal variability in ecosystems significantly impacts species diversity and ecosystem productivity and therefore the evolution of organisms. Different levels of environmental perturbations such as seasonal fluctuations, natural disasters, and global ...
Adami +9 more
core +1 more source
Estimates of genotypic and phenotypic variance, heritability, and genetic advance of horticultural traits in developed crosses of cowpea (Vigna unguiculata [L.] Walp). [PDF]
Front Plant Sci, 2022 Zaki HEM, Radwan KSA.
europepmc +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
, 2017 Estimation of genetic parameters is pertinent as variability within population determines the extent of improvement achieved through crop improvement methods.
Getachew Weldemichael +2 more
semanticscholar +1 more source
Enhanced genetic algorithm-based fuzzy multiobjective strategy to multiproduct batch plant design [PDF]
, 2009 This paper addresses the problem of the optimal design of batch plants with imprecise demands in product amounts. The design of such plants necessary involves how equipment may be utilized, which means that plant scheduling and production must constitute
Aguilar-Lasserre, Alberto +3 more
core +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Journal of Horticultural Sciences, 2015 Variability, heritability, correlation and genetic divergence were studied in 30 strains of dolichos bean (Lablab purpureus L.) for various growth and yield attributing parameters.
T S Dhillon, Ajay Kumar
doaj +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Genetic variability for yield and its components in indian mustard (Brassica juncea L. Czern & Coss) [PDF]
Electronic Journal of Plant Breeding, 2014 Study of 60 genotypes of Indian mustard (Brassica juncea L. Czern & Coss) for 13 different characters revealed considerable variability for all the characters under study.
Neelam Shekhawat, G. C. Jadeja and Jogendra Singh
doaj