Results 31 to 40 of about 538,821 (309)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits [PDF]

open access: gold, 2021
Christopher N. Foley   +6 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

An effective hybrid algorithm for multi-objective flexible job-shop scheduling problem

open access: yesAdvances in Mechanical Engineering, 2018
Genetic algorithm is one of primary algorithms extensively used to address the multi-objective flexible job-shop scheduling problem. However, genetic algorithm converges at a relatively slow speed.
Xiabao Huang, Zailin Guan, Lixi Yang
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Bridge Critical State Search by Using Quantum Genetic Firefly Algorithm

open access: yesShock and Vibration, 2019
When performing flutter analysis through the traditional methods, it is difficult to solve high-order strong nonlinear equations. For overcoming this difficulty, this paper establishes a double-parameter optimization model for searching the flutter ...
Shi-bo Tao, Dian-zhong Liu, Ai-ping Tang
doaj   +1 more source

Diabetic Retinopathy Detection Using Genetic Algorithm‐Based CNN Features and Error Correction Output Code SVM Framework Classification Model [PDF]

open access: hybrid, 2022
Najib Ullah   +6 more
openalex   +1 more source

The genetic algorithm in science

open access: yesPesticide Science, 1995
AbstractAlgorithms developed for use in the study of artificial intelligence also show promise in such quite different fields as the physical and life sciences. These methods may have advantages in speed, scope, or both, over more conventional scientific methods, and expand the range of algorithmic techniques open to the scientist. The mechanism of one
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A genetic-based algorithm for personalized resistance training

open access: yesBiology of Sport, 2016
Association studies have identified dozens of genetic variants linked to training responses and sport-related traits. However, no intervention studies utilizing the idea of personalised training based on athlete’s genetic profile have been conducted ...
N Jones   +6 more
doaj  

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