Results 51 to 60 of about 4,528,698 (293)
Gamma-Ray Spectral Unfolding of CdZnTe-Based Detectors Using a Genetic Algorithm
The analysis of γ-ray spectra can be an arduous task, especially in the case of room temperature semiconductor detectors, where several distortions and instrumental artifacts conceal the true spectral shape.
Nicola Sarzi Amadè +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A genetic-based algorithm for personalized resistance training
Association studies have identified dozens of genetic variants linked to training responses and sport-related traits. However, no intervention studies utilizing the idea of personalised training based on athlete’s genetic profile have been conducted ...
N Jones +6 more
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Population-less Genetic Algorithm? Investigation of Non-dominated Tournament Genetic Algorithm (NTGA2) for multi-objective optimization [PDF]
Michał Antkiewicz, Pawel Myszkowski
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A GPU accelerated hybrid GA-SVM for large scale datasets: Cu-GA-SVM
In this study, CUDA based speed optimization of a hybrid method consisting of Genetic Algorithm and Support Vector Machines has been performed. In machine learning, it is aimed to achieve high accuracy values from the developed methods.
Musa PEKER, Osman ÖZKARACA
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MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Predictive Model for End Aim Temperature of Arc Furnace Based on Hybrid Genetic Algorithm
BP ( Back Propagation) algorithm and genetic algorithm are combined into hybrid genetic algorithm of which the algorithm steps are first to locate a favorable searching region by genetic algorithm, then to search optimal coefficients in the located ...
姜静, 李华德, 孙铁, 姜琳
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