Results 41 to 50 of about 451,148 (267)
Gamma-Ray Spectral Unfolding of CdZnTe-Based Detectors Using a Genetic Algorithm
Sensors, 2020 The analysis of γ-ray spectra can be an arduous task, especially in the case of room temperature semiconductor detectors, where several distortions and instrumental artifacts conceal the true spectral shape.
Nicola Sarzi Amadè +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A genetic-based algorithm for personalized resistance training
Biology of Sport, 2016 Association studies have identified dozens of genetic variants linked to training responses and sport-related traits. However, no intervention studies utilizing the idea of personalised training based on athlete’s genetic profile have been conducted ...
N Jones +6 more
doaj
Population-less Genetic Algorithm? Investigation of Non-dominated Tournament Genetic Algorithm (NTGA2) for multi-objective optimization [PDF]
Annals of computer science and information systems, 2023 Michał Antkiewicz, Pawel Myszkowski
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A GPU accelerated hybrid GA-SVM for large scale datasets: Cu-GA-SVM
Gazi Üniversitesi Fen Bilimleri Dergisi, 2018 In this study, CUDA based speed optimization of a hybrid method consisting of Genetic Algorithm and Support Vector Machines has been performed. In machine learning, it is aimed to achieve high accuracy values from the developed methods.
Musa PEKER, Osman ÖZKARACA
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Procedia Computer Science, 2013 AbstractThe purpose of this paper is to describe and evaluate a new algorithm for optimization. The new algorithm is named the Genetic Flock Algorithm. This algorithm is a type of hybrid of a Genetic Algorithm and a Particle Swarm Optimization Algorithm. The paper discusses strengths and weaknesses of these two algorithms.
Jeffrey Brooks, David L. Hibler
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source