Results 71 to 80 of about 4,528,698 (293)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Nonuniform antenna array design by parallelizing three-parent crossover genetic algorithm

open access: yesEURASIP Journal on Wireless Communications and Networking, 2017
Antenna plays a very important role in wireless communication. Array elements laid out nonuniformly could achieve better frequency reliability and lower sidelobe level than uniform spaced elements.
Xin Zhang, Qinglian Zhang, Xiu Zhang
doaj   +1 more source

A hybrid decision tree/genetic algorithm method for data mining [PDF]

open access: yes, 2004
This paper addresses the well-known classification task of data mining, where the objective is to predict the class which an example belongs to. Discovered knowledge is expressed in the form of high-level, easy-to-interpret classification rules.
Carvalho, Deborah R., Freitas, Alex A.
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Phase Transitions and Symmetry Breaking in Genetic Algorithms with Crossover [PDF]

open access: yes, 2006
In this paper, we consider the role of the crossover operator in genetic algorithms. Specifically, we study optimisation problems that exhibit many local optima and consider how crossover affects the rate at which the population breaks the symmetry of ...
Jennings, N. R.   +4 more
core   +2 more sources

DIPLOID GENETIC ALGORITHM WITH MORTALITY

open access: yesМіжнародний науково-технічний журнал "Проблеми керування та інформатики"
The method of improvement of diploid genetic algorithm via probabilistic limitation of individual’s lifespan is offered. Mean lifespan of individual is determined depending on the population size based on Haldane’s substitution cost estimation.
K.V. Makhotilo
doaj   +1 more source

An immune system based genetic algorithm using permutation-based dualism for dynamic traveling salesman problems [PDF]

open access: yes, 2009
Copyright @ Springer-Verlag Berlin Heidelberg 2009.In recent years, optimization in dynamic environments has attracted a growing interest from the genetic algorithm community due to the importance and practicability in real world applications. This paper
Yang, S   +8 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Genetic algorithms in Forth

open access: yesCoRR, 2018
17 ...
S. I. Khashin, S. E. Vaganov
openaire   +3 more sources

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