Results 71 to 80 of about 451,148 (267)

Analysis of usage of genetic and tabu search algorithms in shop scheduling

open access: yesLietuvos Matematikos Rinkinys, 2008
A wide area of scheduling problem is industrial so-called shop scheduling (Job Shop, Flow Shop and Open Shop) which has important applications in real world industrial problems.
Edgaras Šakurovas   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

An Improved NSGA-III Algorithm Using Genetic K-Means Clustering Algorithm

open access: yesIEEE Access, 2019
The non-dominated sorting genetic algorithm III (NSGA-III) has recently been proposed to solve many-objective optimization problems (MaOPs). While this algorithm achieves good diversity, its convergence is unsatisfactory.
Qingguo Liu   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Optimization method of truss structure size and shape based on harmonic search genetic algorithm

open access: yesJixie qiangdu
In order to improve the traditional design concept and the lack of optimization of genetic algorithm, and promote the development and innovation of the shape optimization of truss structure, according to the basic principles of harmony search algorithm ...
XIE Jun   +4 more
doaj  

An Improved Chaos Genetic Algorithm for T-Shaped MIMO Radar Antenna Array Optimization

open access: yesInternational Journal of Antennas and Propagation, 2014
In view of the fact that the traditional genetic algorithm easily falls into local optimum in the late iterations, an improved chaos genetic algorithm employed chaos theory and genetic algorithm is presented to optimize the low side-lobe for T-shaped ...
Xin Fu   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

基于小生境遗传算法的汽车悬架优化设计研究

open access: yesJixie chuandong, 2013
Improvements on the basis of traditional genetic algorithms,combined with the advantages of niche algorithm and genetic algorithm,a niche genetic algorithm for optimization of mechanical design is proposed.This algorithm is used in real machinery ...
常秋香
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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