Results 31 to 40 of about 3,829,483 (294)

Parameter Selection in Genetic Algorithms [PDF]

Journal of Systemics, Cybernetics and Informatics, 2004
In this study, we provide a new taxonomy of parameters of genetic algorithms (GA), structural and numerical parameters, and analyze the effect of numerical parameters on the performance of GA based simulation optimization applications with experimental ...
Onur BOYABATLI, Ihsan SABUNCUOGLU
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Genetic Operators Applied to Symmetric Cryptography

International Journal of Interactive Multimedia and Artificial Intelligence, 2019
In this article, a symmetric-key cryptographic algorithm for text is proposed, which applies Genetic Algorithms philosophy, entropy and modular arithmetic.
Jefferson Rodríguez, Brayan Corredor, César Suárez   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A comparative study of immune system based genetic algorithms in dynamic environments [PDF]

, 2006
Copyright @ 2006 ACMDiversity and memory are two major mechanisms used in biology to keep the adaptability of organisms in the ever-changing environment in nature.
Yang, S, Shengxiang Yang, Yang, Shengxiang   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Genetic Flock Algorithm

Procedia Computer Science, 2013
AbstractThe purpose of this paper is to describe and evaluate a new algorithm for optimization. The new algorithm is named the Genetic Flock Algorithm. This algorithm is a type of hybrid of a Genetic Algorithm and a Particle Swarm Optimization Algorithm. The paper discusses strengths and weaknesses of these two algorithms.
Jeffrey Brooks, David L. Hibler
openaire   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

DESIGN OPTIMIZATION OF MECHANICAL SYSTEMS USING GENETIC ALGORITHMS

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2003
This papeı- prcsents an algorithnı foı· thedesign of minimum weight of speed reducer., geartrain, subject to a specificd set of constraints.
Hamit SARUHAN, İlyas UYGUR
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source