Results 41 to 50 of about 3,657,954 (286)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Comparative analysis of the method of assignment by classes in GAVaPS

Journal of Computer Science and Technology, 2000
Three alternatives within the method of assignment by classes are presented for the calculation of individuals lifetime in genetic algorithms with varying population size. (GAVaPS). In the proposed strategy (assignment by classes) individuals are grouped
Laura Cristina Lanzarini, Cecilia Verónica Sanz, Marcelo Naiouf, Fernando Romero   +3 more
doaj  

UniSchedApi: A comprehensive solution for university resource scheduling and methodology comparison

TESEA, Transactions on Energy Systems and Engineering Applications
This paper introduces UniSchedApi, an API-based solution that revolutionizes optimized university resource scheduling. The primary focus of the research is the detailed evaluation of two automatic resource allocation methods: Tabu Search (TS) and ...
Alexandra La Cruz, Luis Herrera, Jeisson Cortes, Andrés García, Erika Severeyn   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A SYSTEM FOR REMOTE MONITORING OF THE HUMAN BODY PARAMETERS [PDF]

Carpathian Journal of Electrical Engineering, 2015
We present an invention (pending patent number A 201100939) related to a system that monitors human body parameters, such as heart rate and blood pressure, and when they are out of the regular range, it transmits a remote warning signal along with the ...
Oliviu MATEI, Claudia MATEI, Ioan VLAD, Cristinel COSTEA   +3 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Incremental multiple objective genetic algorithms [PDF]

, 2004
This paper presents a new genetic algorithm approach to multi-objective optimization problemsIncremental Multiple Objective Genetic Algorithms (IMOGA).
Chen, Q, Guan, SU, Chen, Q., Guan, S.-U.
core   +1 more source

GENETIC ALGORITHMS OF WORK DISTRIBUTION

Вестник Донского государственного технического университета, 2018
The tasks of heterogeneous work distribution among heterogeneous executors taking into account operation and switching process costs are investigated. Genetic algorithms of work distribution that can be used for solving various practical tasks both in ...
Andrey R. Aidinyan, Olga L. Tsvetkova
doaj  

DESIGN OPTIMIZATION OF MECHANICAL SYSTEMS USING GENETIC ALGORITHMS

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2003
This papeı- prcsents an algorithnı foı· thedesign of minimum weight of speed reducer., geartrain, subject to a specificd set of constraints.
Hamit SARUHAN, İlyas UYGUR
doaj   +1 more source