Results 71 to 80 of about 813,318 (331)
APPLICATION OF THE DIRECTED MUTATION TO CELLULAR AUTOMATA GENERATION PROCESS [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2014 Cellular automata are widely used for the simulation of discrete systems. However, in most cases creation of controlling cellular automata is done manually, empirically or by exhaustive search. A number of papers describe methods for automatic generation
A. V. Tikhomirov, A. A. Shalyto
doaj
Improving the Performance of Multiobjective Genetic Algorithms: An Elitism-Based Approach [PDF]
, 2020 Giorgio Guariso, Matteo Sangiorgio
openalex +1 more source
Evolutionary Theory and Computerised Genetic Algorithms [PDF]
, 2018 Neo-Darwinism can be usefully studied with the help of a Computerised Genetic Algorithm. Only a mathematical approach can reveal the shortcomings of the current dogma and point the way to a revised definition of the theory of ...
Hough, Derek Philip
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
EXPRESS METHOD OF BARCODE GENERATION FROM FACIAL IMAGES [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2014 In the paper a method of generating of standard type linear barcodes from facial images is proposed. The method is based on use of the histogram of facial image brightness, averaging the histogram on a limited number of intervals, quantization of results
G. A. Kukharev +2 more
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A coarse-grained parallelization of genetic algorithms
IJAIN (International Journal of Advances in Intelligent Informatics), 2018 Genetic algorithms are frequently used to solve optimization problems. However, the problems become increasingly complex and time consuming. One solution to speed up the genetic algorithm processing is to use parallelization. The proposed parallelization
Muhamad Radzi Rathomi, Reza Pulungan
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source