Results 151 to 160 of about 7,627,088 (344)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst +6 morewiley +1 more sourceGenetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort [PDF]
, 2018 Qinchuan Wang, Justin R. Gregg, Jian Gu, Yuanqing Ye, David W. Chang, John W. Davis, Timothy C. Thompson, Jeri Kim, Christopher J. Logothetis, Xifeng Wu +9 moreopenalex +1 more sourceThe newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...Dylan Casey, Zeqian Gao, Joan Boyeswiley +1 more sourceAssociation of genetic variation in COL11A1 with adolescent idiopathic scoliosis [PDF]
, 2023 Hao Yu, Anas M. Khanshour, Aki Ushiki, Nao Otomo, Yoshinao Koike, Elísabet Einarsdóttir, Yanhui Fan, Lilian Antunes, Yared H. Kidane, Reuel Cornelia, Rory Sheng, Yichi Zhang, Jimin Pei, Nick V. Grishin, Bret M. Evers, Jason Pui Yin Cheung, John A. Herring, Chikashi Terao, You‐Qiang Song, Christina A. Gurnett, Paul Gerdhem, Shiro Ikegawa, Jonathan J. Rios, Nadav Ahituv, Carol A. Wise +24 moreopenalex +1 more sourceTrans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
Nature Genetics, 2021 D. Conti, B. Darst, Lilit C Moss, E. Saunders, Xin Sheng, Alisha Chou, F. Schumacher, A. Olama, S. Benlloch, Tokhir Dadaev, M. Brook, A. Sahimi, T. Hoffmann, Atushi Takahashi, K. Matsuda, Y. Momozawa, Masashi Fujita, K. Muir, A. Lophatananon, Peggy Wan, L. Le Marchand, L. Wilkens, V. Stevens, S. Gapstur, B. Carter, J. Schleutker, T. Tammela, C. Sipeky, A. Auvinen, G. Giles, M. Southey, R. MacInnis, C. Cybulski, D. Wokołorczyk, J. Lubiński, D. Neal, J. Donovan, F. Hamdy, Richard M. Martin, B. Nordestgaard, S. F. Nielsen, Maren Weischer, S. Bojesen, M. Røder, P. Iversen, J. Batra, S. Chambers, Leire Moya, L. Horvath, J. Clements, W. Tilley, G. Risbridger, H. Gronberg, M. Aly, R. Szulkin, M. Eklund, T. Nordström, N. Pashayan, A. Dunning, M. Ghoussaini, R. Travis, T. Key, E. Riboli, Jong Y. Park, T. Sellers, Hui-Yi Lin, D. Albanes, S. Weinstein, L. Mucci, E. Giovannucci, S. Lindstrom, P. Kraft, D. Hunter, K. Penney, Constance Turman, C. Tangen, P. Goodman, I. Thompson, R. Hamilton, N. Fleshner, A. Finelli, M. Parent, J. Stanford, E. Ostrander, M. Geybels, S. Koutros, L. Freeman, M. Stampfer, A. Wolk, N. Håkansson, G. Andriole, R. Hoover, M. Machiela, K. D. Sørensen, M. Borre, W. Blot, W. Zheng, E. Yeboah, J. Mensah, Yong-jie Lu, Hong-wei Zhang, Ninghan Feng, Xueying Mao, Yudong Wu, Shan-Chao Zhao, Zan Sun, S. Thibodeau, S. McDonnell, D. Schaid, C. West, N. Burnet, G. Barnett, C. Maier, T. Schnoeller, Manuel Luedeke, A. Kibel, B. Drake, O. Cussenot, G. Cancel-Tassin, F. Menegaux, Thérèse Truong, Y. Koudou, E. John, E. Grindedal, L. Maehle, K. Khaw, S. Ingles, M. Stern, A. Vega, A. Gómez-Caamaño, L. Fachal, B. Rosenstein, S. Kerns, H. Ostrer, M. Teixeira, P. Paulo, Andreia Brandão, S. Watya, Alex Lubwama, J. Bensen, E. Fontham, J. Mohler, Jack A. Taylor, M. Kogevinas, J. Llorca, G. Castaño‐Vinyals, L. Cannon-Albright, C. Teerlink, C. Huff, S. Strom, L. Multigner, P. Blanchet, L. Brureau, R. Kaneva, C. Slavov, V. Mitev, R. Leach, Brandi Weaver, H. Brenner, Katarina Ćuk, B. Holleczek, K. Saum, E. Klein, A. Hsing, R. Kittles, Adam B. Murphy, C. Logothetis, Jeri Kim, S. Neuhausen, L. Steele, Y. Ding, W. Isaacs, B. Nemesure, A. Hennis, J. Carpten, H. Pandha, A. Michael, K. De Ruyck, G. De Meerleer, P. Ost, Jianfeng Xu, A. Razack, Jasmine Lim, S. Teo, Lisa F. Newcomb, D. Lin, J. Fowke, C. Neslund-Dudas, B. Rybicki, M. Gamulin, D. Lessel, T. Kuliš, N. Usmani, S. Singhal, M. Parliament, F. Claessens, S. Joniau, T. Van den Broeck, M. Gago-Domínguez, J. Castelao, M. Martínez, Samantha E. T. Larkin, P. Townsend, Claire Aukim-Hastie, W. Bush, M. Aldrich, D. Crawford, S. Srivastava, J. Cullen, G. Petrovics, G. Casey, M. Roobol, G. Jenster, R. V. van Schaik, Jennifer J. Hu, M. Sanderson, R. Varma, R. Mckean-Cowdin, M. Torres, Nicholas Mancuso, S. Berndt, S. K. Van Den Eeden, D. Easton, S. Chanock, M. Cook, F. Wiklund, H. Nakagawa, J. Witte, R. Eeles, Z. Kote-Jarai, C. Haiman +230 moresemanticscholar +1 more sourceGenetic ancestral patterns in CYP2D6 alleles: structural variants, rare variants, and clinical associations in 479,144 UK Biobank genomes [PDF]
Xiao Jiang, Fengyuan Hu, Xueqing Zoe Zou, Ali Abbasi, Sri V. V. Deevi, Santosh S. Atanur, Amanda O’Neill, Jennifer Harrow, Margarete A. Fabre, Quanli Wang, Slavé Petrovski, William Rae, Oliver S. Burren, Katherine R. Smith +13 moreopenalex +1 more source