Results 161 to 170 of about 8,691,632 (395)

Genetic Association in Myocardial Infarction: Ethnicity; ABO, Rh, Lea, Xga Blood Groups; G6PD Deficiency; and Abnormal Haemoglobins [PDF]

, 1973
N. Saha, C. C. S. Toh, Mahua Ghosh
openalex   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Genetic association of defects in macrophage larvicidal activity and vaccine-induced resistance to Schistosoma mansoni in P strain mice [PDF]

, 1987
Stephanie L. James, Rodrigo Cardoso de Oliveira, Alan Sher, L A Medvitz, R. Dale McCall   +4 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Association of cytokine genetic polymorphism with hepatites B infection evolution in adult patients

Memorias do Instituto Oswaldo Cruz, 2007
The infection by the hepatitis B virus (HBV) has different forms of evolution, ranging from self-limited infection to chronic hepatic disease. The objective of this study was to evaluate the influence of cytokine genetic polymorphisms in the disease ...
Cátia Silene Sversuti Ribeiro, Jeane Eliete Laguila Visentainer, Ricardo Alberto Moliterno   +2 more
doaj  

Immune-checkpoint HLA-G gene polymorphisms, 3’-UTR types and their association with hepatocellular carcinoma and treatment response in Indian population

Frontiers in Immunology
BackgroundHuman leukocyte antigen-G (HLA-G) is a cancer-associated immune checkpoint protein implicated in tumor-driven immune escape mechanisms. This study was undertaken to determine genetic variations at the 3’-UTR of the HLA-G gene that may alter its
Neeti Nadda, Renu Yadav, Neelanjana Roy, Nita Singh, Sonu Kumar, Shashi Bala Paul, Shivanand Gamanagatti, Anoop Saraya, Shalimar, Baibaswata Nayak   +9 more
doaj   +1 more source

Genetic studies in multiple myeloma. II. Immunoglobulin allotype associations [PDF]

, 1985
Stephen H. Leech, Rebecca J. Brown, Moses S. Schanfield   +2 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis

Frontiers in Public Health
ObjectiveAlthough smoking and osteoarthritis (OA) have been linked in a number of studies, the exact cause of the association is still unknown and the conclusion is controversial. The purpose of this study was to use Mendelian randomization (MR) analysis
Qiang Xiao, Susu Dong, Yafen Tan, Xuan Zhang, Lu Yao, Qiuping Li, Tianli Wang   +6 more
doaj   +1 more source

The genetic susceptibility to type 1 (insulin-dependent) diabetes: Analysis of the HLA-DR association [PDF]

, 1983
Eckhard Wolf, K.M. Spencer, A G Cudworth
openalex   +1 more source