Results 171 to 180 of about 7,627,088 (344)

Association of ANKK1 polymorphism with schizophrenia: negative findings from a genetic approach

, 2020
О.Ю. Федоренко, Diana Z. Paderina, Ivan V. Pozhidaev, Anastasiia S. Boiko, Elena G. Kornetova, Н. А. Бохан, Svetlana А. Ivanova   +6 more
openalex   +2 more sources

Genetic Architecture Reconciles Linkage and Association Studies of Complex Traits

, 2023
Loïc Yengo
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Unveiling Genetic Associations: Investigating CLDN16, GRID2, NRG3, and CACNG4 Gene Polymorphisms with Insulin Resistance Risk Among Normal BMI Individuals in the Indian Population [PDF]

Sabitha Thummala, Junaid Ahmed Khan Ghori, Sarah Fathima, Katherine Saikia, Nithya Kruthi, Shanti Lakshmi Duraimani, AR Balamurali, Rahul Ranganathan   +7 more
openalex   +1 more source

Genetic association of mosaic loss of chromosome Y with prostate cancer in men of European and East Asian ancestries: a Mendelian randomization study [PDF]

, 2023
Takuro Kobayashi, Tsuyoshi Hachiya, Yoshihiro Ikehata, Shigeo Horie   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

New Insights into the Genetic Association of Lipids and Lipid-Modifying Target Genes with Pancreatitis. [PDF]

MedComm (2020)
Yao L, Yang X, Sutton R, Xia Q, Huang W.
europepmc   +1 more source

Genetic association of type 2 diabetes mellitus and glycaemic factors with primary tumours of the central nervous system [PDF]

Yongxue Li, Lihao Lin, Wenhui Zhang, Yan Wang, Yi Guan   +4 more
openalex   +1 more source

Genetic association study of fatal pulmonary embolism [PDF]

, 2020
Lisa Meißner, Peter Schürmann, Thilo Dörk, L. Hagemeier, Michael Klintschar   +4 more
openalex   +1 more source

Credible genetic associations?

International journal of molecular epidemiology and genetics, 2011
The proliferation in genetic association studies, and the recurring failure of initially promising findings to robustly replicate, demonstrates the need for stringent standards to ensure the identification of credible associations. The Human Genome Epidemiology Network has recently published intermin guideliness on evidential criteria for genetic ...
openaire   +1 more source