Results 211 to 220 of about 8,691,632 (395)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Research of caspase-dependent mechanisms of apoptosis induction and the activity of peroxidation and antioxidant defense in the thyroid tissue of patients with nodular forms of goiter combined with autoimmune thyroiditis and thyroid adenoma depending on the allelic status of Bcl-2 (rs17759659), CTLA-4 (rs231775), APO-1 / Fas (rs2234767) genes

open access: yesJournal of Education, Health and Sport, 2017
The aim of the work is to analyze the mechanisms of caspase-dependent apoptosis and pro- and antioxidant activity in the thyroid tissue homogenate in patients with in patients with nodular goiter with autoimmune thyroiditis and thyroid adenoma ...
M. I. Sheremet
doaj  

Association of genetic polymorphism of glutathione S-transferase M1, T1 and N-acetyltransferase 1 with lung cancer [PDF]

open access: bronze, 1999
Seung Joon Lee   +10 more
openalex   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Genetics of ANCA-associated vasculitides.

open access: yesCleveland Clinic Journal of Medicine, 2002
Coen A. Stegeman   +2 more
openaire   +4 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Genetic association of intelligence with longevity in Drosophila melanogaster. [PDF]

open access: yesPLoS One
Khan M   +5 more
europepmc   +1 more source

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