Results 211 to 220 of about 2,761,484 (346)

The Alpha‐1 Association Genetic Counseling Program: An Innovative Approach to Service [PDF]

open access: bronze, 2011
Dawn McGee   +4 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Genetic association and functional implications of AhR gene polymorphism on preeclampsia. [PDF]

open access: yesFront Cardiovasc Med
Jiang H   +6 more
europepmc   +1 more source

Weighing the Genetic Risk: Associations Between Polygenic Risk Scores for Cardiometabolic Phenotypes and Adolescent Depression and Body Dissatisfaction

open access: gold
Krista M. Ekberg   +8 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Genetic association of intelligence with longevity in Drosophila melanogaster. [PDF]

open access: yesPLoS One
Khan M   +5 more
europepmc   +1 more source

American Genetic Association [PDF]

open access: yesZeitschrift für Induktive Abstammungs- und Vererbungslehre, 1915
openaire   +1 more source

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