Results 271 to 280 of about 8,825,337 (378)

Genomic Control, a New Approach to Genetic-Based Association Studies [PDF]

, 2001
Bernie Devlin, Kathryn Roeder, Larry Wasserman   +2 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Erectile Dysfunction in Diabetes Mellitus: A Comprehensive Narrative Review of Pathophysiology, Genetic Association Studies and Therapeutic Approaches. [PDF]

Endocrinol Diabetes Metab
Hostnik B, Tonin G, Janež A, Klen J.
europepmc   +1 more source

Evidence for Genetic Factors Explaining the Association Between Birth Weight and Low-Density Lipoprotein Cholesterol and Possible Intrauterine Factors Influencing the Association Between Birth Weight and High-Density Lipoprotein Cholesterol: Analysis in Twins [PDF]

, 2001
Richard G. IJzerman, Coen D.A. Stehouwer, Mirjam M. van Weissenbruch, Eco J. C. de Geus, Dorret I. Boomsma   +4 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

RETRACTION: Genetic Association between Asthma and Alopecia Areata: A Two-Sample Mendelian Randomization Study. [PDF]

Skin Res Technol
europepmc   +1 more source

Potential Causal Relationships Between Circulating Micronutrient Levels and Multiple Neuroimmune Diseases: A Genetic Association Analysis. [PDF]

Brain Behav
Chen L, Wu X, Wang K, Zhou X, Mou Y, Liu Z, Shen Z, Lv Z, Lv L.   +8 more
europepmc   +1 more source

Genetic analysis of pancreatic duct hyperplasia in Otsuka Long–Evans Tokushima Fatty rats: Possible association with a region on rat chromosome 14 that includes the disrupted cholecystokinin‐A receptor gene [PDF]

, 2001
N Kanemoto, Mari Kondo, Tomoyuki Iwanaga, Haretsugu Hishigaki, Toshihide Ono, Ayako Mizoguchi‐Miyakita, Keiko Oga, Atsushi B. Tsuji, Shiro Okuno, Takeshi Watanabe, Masato Nose, Akira Tanigami   +11 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

The Genetic Association Between Neocortical Volume and General Cognitive Ability Is Driven by Global Surface Area Rather Than Thickness.

Cerebral Cortex, 2015
E. Vuoksimaa, M. Panizzon, Chi-Hua Chen, Mark Fiecas, L. Eyler, C. Fennema-Notestine, D. Hagler, B. Fischl, C. Franz, A. Jak, M. Lyons, M. Neale, D. Rinker, W. Thompson, M. Tsuang, A. Dale, W. Kremen   +16 more
semanticscholar   +1 more source