Results 181 to 190 of about 2,429,135 (273)

Random effect based tests for multinomial logistic regression in genetic association studies. [PDF]

Genet Epidemiol, 2021
He Q, Liu Y, Liu M, Wu MC, Hsu L.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Adapting PRISMA Guidelines to Enhance Reporting Quality in Genetic Association Studies: A Framework Proposal. [PDF]

Asian Pac J Cancer Prev
Nezameslami R, Nezameslami A, Mehdikhani B, Mosavi-Jarrahi A, Shahbazi A, Rahmani A, Masoudi A, Yeganegi M, Akhondzardaini R, Bahrami M, Aghili K, Neamatzadeh H.   +11 more
europepmc   +1 more source

Genetic Association Studies of Age-Related Traits: New Perspectives. [PDF]

Adv Geriatr Med Res, 2021
Kulminski AM.
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Genetic association studies using disease liabilities from deep neural networks. [PDF]

Am J Hum Genet
Yang L, Sadler MC, Altman RB.
europepmc   +1 more source

Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. [PDF]

Sci Rep, 2021
Brandes N, Linial N, Linial M.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Association of Brain-derived Neurotrophic Factor Polymorphisms With Alcohol Use Disorder: An Updated Meta-Analysis of Genetic Association Studies. [PDF]

Brain Behav
Jenwitheesuk A, Pabalan N, Tapanadechopone P, Jarjanazi H, Arunphalungsanti K, Tharabenjasin P.   +5 more
europepmc   +1 more source

Systematic review and meta-analysis of genetic association studies of pelvic organ prolapse. [PDF]

Int Urogynecol J, 2022
Allen-Brady K, Chua JWF, Cuffolo R, Koch M, Sorrentino F, Cartwright R.   +5 more
europepmc   +1 more source